Endoscopic Endonasal Transphenoidal Approach for Pituitary Adenomas: Outcomes of Our Center

Abstract

Poster PresentationsP163 at 2 hours after irradiation. EGR-1 knock-down cells displayed decreased radiation-induced apoptosis, compared with control cells in cell apoptosis assay. Cleaved caspase 3, cleaved caspase 7, cleaved PARP, and Bax activation was decreased by EGR-1 knock-down after irradiation.Conclusions: EGR-1 had abundant expression in human HNSCC tissue. EGR-1 knock-down decreased radiationinduced apoptosis through caspase 3, caspase, 7, PARP, and Bax. EGR-1 may play an important role in treatment response after radiation therapy in human HNSCC.