Endoscopic Findings of Gastro-Esophageal Reflux Disease in Elderly and Younger Age Groups

Abstract

Objective: To determine and compare the clinical features and endoscopic findings of gastro-esophageal reflux disease (GERD) in elderly and younger age groups.Materials and Methods: The clinical and endoscopic features were evaluated for all patients with GERD between January 2017 and September 2020. The criteria for inclusion were being aged over 65 and under 50 years and having an upper gastrointestinal endoscopy with reflux symptoms resistant to ppi theraphy. The exclusion criteria included prior surgery, age under 18 years, and pregnancy. The diagnosis of GERD was made according to the patients' symptoms. The SPSS 11.0 for Windows pocket program was used for statistical analysis.Results: Two hundred eighty-six patients aged over 65 years and 261 patients aged below 50 years were enrolled in this study. The mean age of the older group was 68.2 ± 4.5 years and the mean age of the young group was 38 ± 7.2 years. The male/female ratio was 5/3 and 2/1 in the young and older groups, respectively. The older patients had less severe and rare typical symptoms than the young patients. However, significantly more serious endoscopic findings were noted in the older patients compared with the younger patients.Conclusion: The older and young patients with GERD were predominantly male and typical reflux problems were less common in older patients with GERD. Older patients had more important endoscopic findings such as hernia, esophagitis, and cancer.

Indications and Findings of Upper Gastrointestinal Endoscopy in Elderly Patients in Parakou, Republic of Benin

“…The elderly subjects who underwent UGIE in Parakou were often male (sex ratio = 1.26), contrary to the findings made in Malian, Ivorian, Senegalese, Togolese and Turkish studies where the sex ratios were 0.9, 0.88, 0.82, 0.66 and 0.54, respectively [2] [3] [7] [8] [10].…”

“…In a Turkish study of gastroesophageal reflux disease, elderly patients rarely had typical and severe symptoms compared to younger patients. However, significantly more severe endoscopic lesions were observed in older patients compared to younger patients [7]. In Benin, more precisely in the northern part, few data are available on gastrointestinal endoscopy in elderly subjects.…”

Factors Associated with Belching and Retching during Esophagogastroduodenoscopy and Their Effects on Z-Line Appearance

“…The LA classification system focuses on the size of mucosal breaks, which is defined as an area of slough or erythema with a discrete lined demarcation from the adjacent normal-looking mucosa. 9,26 As shown in Fig. 1, the change of Z-line appearance between insertion and withdrawal phase did occur in some cases resulting in the change of LA classification, even though the statistical significance was not observed.…”

Thyroid disorders and gastrointestinal dysmotility: an old association

“…A changed esophageal motility, results in impeding the reflux acid clearance from distal esophagus ( Lin et al, 2019 ). Greater GERD duration causes increased erosive esophagitis, strictures, ulceration, and Barrett’s esophagus ( Lin et al, 2019 ; Adanir et al, 2021 ). Besides, the typical GERD symptoms, reflux disease needs consideration in patients with nausea/vomiting, chronic cough, wheezing, and anorexia.…”