With the development of a special quartz fiberoptic transmission system, the application of laser energy through an endoscope became possible. Now, endoscopic laser therapy is widely used for gastrointestinal bleeding, and gastrointestinal neoplasm, and we have removed broad-based gastric polyps using an endoscopic Nd:YAG laser in 12 patients between January and December 1985.The size of the polyps ranged from 0.2 cm to 1.0 cm in diameter. The most frequent location for the polyp was in the antrum (7 cases) and followed by the fundus (5 cases).The application number of laser energy was from 6 to 58 and the small lesions of the 10 patients were completely ablated by the first endoscopic laser therapy.Follow-up endoscopy in all patients revealed no new polyp formation, but all patients had a residual ulcer at the end of the first week post polypectomy, and ulcers were healed by the fifth week of follow up.