Endoscopic nephrectomy and kidney resection in children with renal cell carcinoma. Description of clinical cases and literature review

Abstract

In spite of the fact that nephoblastoma is a most common pediatric renal tumor, there are periods, during which other renal malignancies are prevalent. Renal cell carcinoma (RCC) becomes increasingly more prevalent with age and has to be reckoned with while choosing diagnostic algorithms and treatment tactics in adolescents.We present two cases of adolescents with localized RCC. In both cases laparoscopic interventions, nephrectomy and tumor resection, were used without pre-operative chemotherapy. The treatment decision on initial surgical treatment was based on visualization results, in one case additional data was provided by fine needle biopsy.These cases highlight the importance of differential diagnosis and visualization data-based treatment interventions in adolescents with renal tumors. The fine needle biopsy may provide some additional data which potentially may allow implying less traumatic laparoscopic surgery and potentially allow nephron-sparing interventions.