endoscopic study on portal hypertensive colopathy in cirrhotic patients

Abstract

Background and Aim: Liver Cirrhosis patients are more prone to lower gastrointestinal (GI) bleeding hypothetically caused by portal hypertensive colopathy (PHC) and anorectal varices (ARVs). The present study aimed to determine the incidence of colopathic lesions and investigate their association with cirrhosis severity and portal hypertensive colopathy manifestation. Patients and Methods: This cross-sectional study was carried out on 80 liver cirrhosis patients in the Department of Gastrointestinal, CMH Hospital Lahore from January 2021 to December 2022. Individuals aged >18 years with liver cirrhosis were enrolled. Each individual underwent laboratory, clinical, and ultrasonographic examinations. Upper gastrointestinal endoscopy was used to detect the PHC. Based on the colopathic lesions severity, patients were categorized into three grades: grade I (colonic mucosa), grade II (mucosa with mosaic-like pattern), and grade III (angiodysplasia-like colon lesions). SPSS version 27 was used for data analysis. Results: The overall mean age was 48.62±5.6 years with an age range 19 to 70 years. Of the total patients, there were 60 (75%) male and 20 (25%) females. Child-Pugh classification of patients were as follows: Class A 16 (20%), Class B 29 (36.3%), and Class C 35 (43.7%).