Endoscopic submucosal dissection comparing with surgical resection in patients with early gastric cancer – A single center experience in Taiwan

Hong, Tzu-Chan; Liou, Jyh‐Ming; Yeh, Chi‐Chuan; Yen, Hung-Hsuan; Wu, Ming–Shiang; Lai, I-Rue; Chen, Chien-Chuan

doi:10.1016/j.jfma.2020.08.027

Cited by 17 publications

(14 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recurrence of gastric cancer was evaluated in 18 studies ( 13 , 16 – 19 , 22 , 25 – 27 , 29 – 32 , 34 , 36 , 38 – 40 ) totaling 9245 patients (4262 in the ER and 4983 in the surgery group). The results showed lower incidence of recurrence in the group who underwent surgery (RD = 0.07, 95%CI = 0.06, 0.08; I² = 15%; p < 0.00001), representing a number need to harm (NNH) of 14.28 ( Figure 6 ).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Endoscopic Resection Versus Surgery in the Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis

et al. 2022

View full text Add to dashboard Cite

Background and AimEndoscopic resection (ER) is the preferred approach to treat early gastric cancer (EGC) in patients without suspected lymph node involvement and that meet the criteria for ER. Surgery is a more aggressive treatment, but it may be associated with less recurrence and the need for reintervention. Previous meta-analyses comparing ER with surgery for EGC did not incorporate the most recent studies, making accurate conclusions not possible.MethodsThis systematic review and meta-analysis aimed to examine complete resection, length of hospital stay (LOHS), adverse events (AEs), serious AEs, recurrence, 5-year overall survival (OS), and 5-year cancer-specific survival (CSS) in patients with EGC.ResultsA total of 29 cohorts studies involving 20559 patients were included. The ER (n = 7709) group was associated with a lower incidence of AEs (RD = -0.07, 95%CI = -0.1, -0.04, p < 0.0001) and shorter LOHS (95% CI -5.89, -5.32; p < 0,00001) compared to surgery (n = 12850). However, ER was associated with lower complete resection rates (RD = -0.1, 95%CI = -0.15, -0.06; p < 0.00001) and higher rates of recurrence (RD = 0.07, 95%CI = 0.06; p < 0.00001). There were no significant differences between surgery and ER in 5-year OS (RD = -0.01, 95%CI = -0.04, 0.02; p = 0.38), 5-year CSS (RD = 0.01, 95%CI = 0.00, 0.02; p < 0.17), and incidence of serious AEs (RD = -0.03, 95%CI = -0.08, 0.01; p = 0.13).ConclusionsER and surgery are safe and effective treatments for EGC. ER provides lower rates of AEs and shorter LOHS compared to surgery. Although ER is associated with lower complete resection rates and a higher risk of recurrence, the OS and CSS were similar between both approaches.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42021255328.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Fourteen studies (12,14,16,19,22,23,25,26,28,34,35,(38)(39)(40) were included in this analysis, totaling 10602 patients (3824 in the ER group and 6778 in the SG group). Complete resection rate was higher in the SG group (RD = -0.1, 95%CI = -0.15, -0.06; I² = 93%; p < 0.00001) (Figure 2).…”

Section: Complete Resectionmentioning

confidence: 99%

Endoscopic Resection Versus Surgery in the Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The definition of early gastric cancer is controversial. In the fourth edition, WHO defined early gastric cancer as a cancer with definite invasion, which was limited to the mucosa and submucosa, regardless of lymph node metastasis 38 . However, the definition of early gastric cancer has been deleted in the fifth edition.…”

Section: Discussionmentioning

confidence: 99%

Is cardia cancer a special type of gastric cancer? A differential analysis of early cardia cancer and non-cardia cancer

Lv¹,

Liang²,

Wu³

et al. 2021

J. Cancer

View full text Add to dashboard Cite

Background: The prognosis of early cardia cancer and non-cardia cancer is still controversial. It is difficult to collect a large number of cases with complete information in clinical practice. Our study was aimed to identify the differences in clinicopathological characteristics and outcomes of early cardia gastric cancer and non-cardia gastric cancer. Methods: All cases analyzed were from Surveillance, Epidemiology, and End Results database. The data of the patients with early gastric cancer from 2004 to 2010 was retrospectively analyzed. Patients were distributed to cardia cancer group and non-cardia cancer group. Univariate and multivariate analyses were performed to examine differences between groups. The competitive risk model was made to compare the association with cardia cancer and non-cardia cancer about the causes of death. Propensity score matching (PSM) was performed to reduce the bias. Results: We found that cardia cancer was more common in male patients and the White than that in non-cardia cancer at early stage, signet ring cell carcinoma was more common in non-cardia cancer, and the differentiation of non-cardia cancer was worse. Univariate analysis showed that age, marital status, race, tumor location, histology, grade, stage, and operation or not can determine the prognosis. And the prognosis of patients with cardia cancer was worse than that of non-cardia cancer, according to lymph node metastasis and the depth of tumor invasion. Multivariate analysis showed cardia cancer was an independent prognostic factor for poor prognosis. After PSM, cardia cancer still exhibited poor prognosis. Conclusions: At early stage, cardia cancer had a poor prognosis compared with non-cardia cancer. The prevention and treatment of early cardia cancer need to be seriously treated.

show abstract

“…The doctor must watch the full film in order, even though the bulk of the images is filled with meaningless information. This frequently leads to misdiagnosis because of incompetence or carelessness [ 8 ] among the doctors.…”

Section: Introductionmentioning

confidence: 99%

A Robust Deep Model for Classification of Peptic Ulcer and Other Digestive Tract Disorders Using Endoscopic Images

et al. 2022

View full text Add to dashboard Cite

Accurate patient disease classification and detection through deep-learning (DL) models are increasingly contributing to the area of biomedical imaging. The most frequent gastrointestinal (GI) tract ailments are peptic ulcers and stomach cancer. Conventional endoscopy is a painful and hectic procedure for the patient while Wireless Capsule Endoscopy (WCE) is a useful technology for diagnosing GI problems and doing painless gut imaging. However, there is still a challenge to investigate thousands of images captured during the WCE procedure accurately and efficiently because existing deep models are not scored with significant accuracy on WCE image analysis. So, to prevent emergency conditions among patients, we need an efficient and accurate DL model for real-time analysis. In this study, we propose a reliable and efficient approach for classifying GI tract abnormalities using WCE images by applying a deep Convolutional Neural Network (CNN). For this purpose, we propose a custom CNN architecture named GI Disease-Detection Network (GIDD-Net) that is designed from scratch with relatively few parameters to detect GI tract disorders more accurately and efficiently at a low computational cost. Moreover, our model successfully distinguishes GI disorders by visualizing class activation patterns in the stomach bowls as a heat map. The Kvasir-Capsule image dataset has a significant class imbalance problem, we exploited a synthetic oversampling technique BORDERLINE SMOTE (BL-SMOTE) to evenly distribute the image among the classes to prevent the problem of class imbalance. The proposed model is evaluated against various metrics and achieved the following values for evaluation metrics: 98.9%, 99.8%, 98.9%, 98.9%, 98.8%, and 0.0474 for accuracy, AUC, F1-score, precision, recall, and loss, respectively. From the simulation results, it is noted that the proposed model outperforms other state-of-the-art models in all the evaluation metrics.

show abstract

Endoscopic submucosal dissection comparing with surgical resection in patients with early gastric cancer – A single center experience in Taiwan

Cited by 17 publications

References 18 publications

Endoscopic Resection Versus Surgery in the Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis

Endoscopic Resection Versus Surgery in the Treatment of Early Gastric Cancer: A Systematic Review and Meta-Analysis

Is cardia cancer a special type of gastric cancer? A differential analysis of early cardia cancer and non-cardia cancer

A Robust Deep Model for Classification of Peptic Ulcer and Other Digestive Tract Disorders Using Endoscopic Images

Contact Info

Product

Resources

About