“…Color flow Doppler can be used prior to EUS-FNA to help avoid vessels overlying the proposed path of the aspiration needle such as are seen when there is underlying portal vein or splenic vein obstruction. Similarly to CT and ultrasound-guided FNA or biopsy, the overall complication rate secondary to EUS-FNA of the pancreas is about 1-2% 6,8,58,61,64 . The major complications reported with EUS-FNA are bleeding, pancreatitis, and infection but mortality is very rare 65 that is more likely when the patient has portal hypertension.…”