Endoscopy in Gastrointestinal Bleeding

Forrest, JohnA.H.; Finlayson, N.; Shearman, D. J. C.

doi:10.1016/s0140-6736(74)91770-x

Cited by 844 publications

(440 citation statements)

References 6 publications

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“…Of the 1,152 patients with bleeding gastric ulcer, those treated with endoscopic hemostasis using a heater probe totaled 1,026 (89.1%). Forrest classification of bleeding [1] were due to multi-organ failure and three were due to either infectious or malignant disease. Four deaths were due to bleeding, of which two were due to unrelated conditions (pulmonary hemorrhage, n=1; aortic rupture, n=1).…”

Section: Resultsmentioning

confidence: 99%

Clinical outcome of endoscopic hemostasis with heater probe coagulation for bleeding gastric ulcer

Inoué¹,

Fujino²,

Onodera³

et al. 2014

Gasteroentrol Intest Syst

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We reviewed 1,152 patients with bleeding gastric ulcer treated at our institution between 1987 and 2011. Of these, 1,026 patients (89.1%) underwent endoscopic hemostasis. Forrest classification for bleeding ulcers in these cases was as follows: Ia, 188 patients (18.3%); Ib, 114 patients (11.1%); and IIa, 665 patients (64.8%). Endoscopic treatment proved successful in 1,023 patients (99.7%), including 70 patients (6.8%) who experienced re-bleeding. There were 19 deaths (1.9%), and 3 patients (0.3%) underwent surgical procedures. No surgical procedures were performed after 1994.

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Section: Resultsmentioning

confidence: 99%

Clinical outcome of endoscopic hemostasis with heater probe coagulation for bleeding gastric ulcer

Inoué¹,

Fujino²,

Onodera³

et al. 2014

Gasteroentrol Intest Syst

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“…[3][4][5] High risk lesions such as actively bleeding ulcers, non-bleeding visible vessels (NBVV) and adherent clots (Table III) require effective aggressive intervention to reduce re-bleeding which is associated with a 5-16 fold increase in mortality. 6,7 The re-bleeding rate of ulcers with a clean base or red or blue spots are low and endoscopic intervention is usually not recommended.…”

Section: Risk Assessment and Initial Managementmentioning

confidence: 99%

Nonvariceal Upper Gastrointestinal Bleeding

Ferguson

Mitchell²

2004

Endoscopy

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A study in the Netherlands examined recent time trends in the incidence and outcome of upper gastrointestinal bleeding between the periods 1993-94 and 2000 [1]. The incidence of acute upper gastrointestinal bleeding decreased from 61.7 per 100 000 in 1993-94 to 47.7 per 100 000 persons annually in 2000, corresponding to a 23 % decrease in the incidence after age adjustment (95 % CI, 15 % to 30 %). Despite more frequent use of combination treatment, more frequent endoscopic interventions to treat ulcers with adherent clots, and a higher rate of protonpump inhibitor (PPI) use in the second period, the rebleeding rate (16 % vs. 15 %) and mortality rate (14 % vs. 13 %) did not differ between the two periods. Ulcer bleeding remained the most frequent cause of bleeding, at 40 % (1993-94) and 46 % (2000). Almost half of all patients with peptic ulcer bleeding were using nonsteroidal anti-inflammatory drugs (NSAIDs) or aspirin. Re-bleeding was similarly high among patients with peptic ulcer bleeding in both groups (20 % and 22 %, respectively). Increasing age, presence of severe comorbidities, and rebleeding were associated with higher mortality. An analysis of secular trends in hospitalization and mortality rates from peptic ulcer disease, upper gastrointestinal bleeding, and any gastrointestinal bleeding was published using data from the National Hospital Discharge Survey [2]. These rates were compared with sales of NSAIDs, aspirin, and acid-suppression medications from 1992 to 1999. Annual rates of hospitalization and mortality per 100 000 population for peptic ulcer disease declined from 205 to 165 and 7.7 to 6.0, respectively; the calendar year correlated negatively with both peptic ulcer disease hospitalization rates (P = 0.007) and mortality rates (P = 0.058). Sales of acid-suppression medications correlated negatively with peptic ulcer disease hospitalization rates (P = 0.037) and mortal

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“…If lesions were detected they were characterized by assessing their type [90], number, bleeding activity [34], localization and expansion. A photograph was taken via the endoscope.…”

Section: Groups Treated By Cimetidine and Regimen Of Drug Administratmentioning

confidence: 99%

Histamine and stress ulcer: New components in organizing a sequential trial on cimetidine prophylaxis in seriously Ill patients and definition of a special group at risk (severe polytrauma)

et al. 1980

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Endoscopy in Gastrointestinal Bleeding

Cited by 844 publications

References 6 publications

Clinical outcome of endoscopic hemostasis with heater probe coagulation for bleeding gastric ulcer

Clinical outcome of endoscopic hemostasis with heater probe coagulation for bleeding gastric ulcer

Nonvariceal Upper Gastrointestinal Bleeding

Histamine and stress ulcer: New components in organizing a sequential trial on cimetidine prophylaxis in seriously Ill patients and definition of a special group at risk (severe polytrauma)

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