Endovascular Stents in Pulmonary Valve and Artery in Swine: Feasibility Study of MR Imaging–guided Deployment and Postinterventional Assessment

Abstract

MR imaging has the potential to guide stent placement in the pulmonary valve or artery and to evaluate flow volume within the stent lumen after the intervention.

Magnetic Resonance Imaging Analysis of Right Ventricular Pressure-Volume Loops

“…[12][13][14] In the present study, we used this approach to perform invasive RV pressure measurements with flow-directed catheters guided under MR fluoroscopy. Simultaneously, ventricular volumes were assessed by use of cine MRI.…”

MR‐guided intravascular interventions: Techniques and applications

“…The development and application of MRI as a guidance tool for endovascular and endoluminal interventions is furthermore motivated by the potential of MRI to acquire relevant morphologic and functional information that cannot be retrieved with other methods. In particular, the measurement of blood flow and perfusion (for example, after stent implantation in the carotid or renal artery) (19) or diffusion (eg, during embolizations) (20) might enable an early evaluation of the therapeutic success during the intervention, thus enabling therapeutically relevant decision-making with the patient still on the table.…”

“…In vessels with atherosclerotic plaques interventional MRI has the potential to visualize the morphology of both the vessel wall and the surrounding tissue (2,9,19,(21)(22)(23)(24)(25), whereas conventional angiography is only able to delineate the vessel lumen. The advantages of this information are clear when one considers that the dangers associated with atherosclerosis are not only caused by luminal narrowing but are also dependent on the structure of the vessel wall.…”

“…An advantage of utilizing microcoils is the possibility to use the MR signal not only for instrument tracking but also for endovascular imaging or functional studies (19,(23)(24)(25). If, for example, the signals of two solenoid coils are combined, both tracking of the catheter as well as high-resolution imaging of the vessel wall is possible (9,54).…”

“…A possible candidate for such an application is the MR-guided targeted injection of cellular material (eg, stem cells or myoblasts) into the vessel wall (81) or the infarcted myocardium (2,19). Under conventional fluoroscopy neither the differentiation between infarcted and viable myocardium nor the reliable tracking of the injected cells is possible (82).…”