Pilot diesel ignition is an effective approach for achieving efficient and clean combustion of natural gas. In this study, a rapid compression and expansion machine (RCEM) was constructed for examining diesel-ignited premixed methane combustion. The effects of the methane equivalence ratio and pilot diesel mass on the combustion process of diesel-ignited premixed methane gas were investigated. The results show that the combustion process can be divided into two stages: diesel dominance and premixed methane combustion. An increase in the methane equivalence ratio inhibits diesel combustion, leading to delayed CA10 and OH radical generation. However, it enhances premixed methane flame propagation and improves the heat release rate, resulting in a shorter combustion duration. An increase in the pilot diesel mass contributes to a larger flame area and higher OH generation intensity in the ignition region; however, too large a diesel mass inhibits methane flame propagation towards the diesel nozzle due to an extended injection duration. In conclusion, a larger pilot diesel mass can achieve better overall combustion performance, but excessive amounts may be counterproductive.