Engineering Inhalable Therapeutic Particles: Conventional and Emerging Approaches
Aditi Negi,
Shubham Nimbkar,
Jeyan Arthur Moses
Abstract:Respirable particles are integral to effective inhalable therapeutic ingredient delivery, demanding precise engineering for optimal lung deposition and therapeutic efficacy. This review describes different physicochemical properties and their role in determining the aerodynamic performance and therapeutic efficacy of dry powder formulations. Furthermore, advances in top-down and bottom-up techniques in particle preparation, highlighting their roles in tailoring particle properties and optimizing therapeutic ou… Show more
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