“…However, the current focus on biomass as a replacement for fossil fuels may hinder this reforestation effort [414]. Hence, there is a pressing need for alternative substrates, focusing on waste degradation, such as the use of lignocellulosic biomass [187,415,416], and the capture and conversion of C1 gases [211,417,418,419]. Although biotechnology is now centered on the production of high-value-added products, establishing bio-based production of bulk chemicals and fuels will have a more significant impact on reducing greenhouse gas emissions [14,24].…”