Enhanced Bacteriostatic Properties of Ti Alloys by Surface Nitriding

Fu, Le; Rajaseka, Karthik; Katsaros, Ioannis; Liu, Yihong; Wang, Helen; Engqvist, Håkan; Xia, Wei

doi:10.1007/s44174-023-00067-y

Cited by 2 publications

(1 citation statement)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Silicon nitride has been found to have antibacterial effects on Gram-positive and Gram-negative bacteria. A lot of in vitro studies have demonstrated the antibacterial activity of silicon nitride against different microorganisms such as Escherichia coli, Staphylococcus epidermidis, and Porphyromonas gingivalis [23,[25][26][27][28][29][30][31][32]. Silicon nitride also exhibits excellent antibacterial properties in animals [33].…”

Section: Introductionmentioning

confidence: 99%

Silicon Nitride Bioceramics Sintered by Microwave Exhibit Excellent Mechanical Properties, Cytocompatibility In Vitro, and Anti-Bacterial Properties

He,

Liu,

Zeng

et al. 2023

JFB

View full text Add to dashboard Cite

Silicon nitride is a bioceramic with great potential, and multiple studies have demonstrated its biocompatibility and antibacterial properties. In this study, silicon nitride was prepared by a microwave sintering technique that was different from common production methods. SEM and pore distribution analysis revealed the microstructure of microwave-sintered silicon nitride with obvious pores. Mechanical performance analysis shows that microwave sintering can improve the mechanical properties of silicon nitride. The CCK-8 method was used to demonstrate that microwave-sintered silicon nitride has no cytotoxicity and good cytocompatibility. From SEM and CLSM observations, it was observed that there was good adhesion and cross-linking of cells during microwave-sintered silicon nitride, and the morphology of the cytoskeleton was good. Microwave-sintered silicon nitride has been proven to be non-cytotoxic. In addition, the antibacterial ability of microwave-sintered silicon nitride against Staphylococcus aureus and Escherichia coli was tested, proving that it has a good antibacterial ability similar to the silicon nitride prepared by commonly used processes. Compared with silicon nitride prepared by gas pressure sintering technology, microwave-sintered silicon nitride has excellent performance in mechanical properties, cell compatibility, and antibacterial properties. This indicates its enormous potential as a substitute material for manufacturing bone implants.

show abstract

Section: Introductionmentioning

confidence: 99%

Silicon Nitride Bioceramics Sintered by Microwave Exhibit Excellent Mechanical Properties, Cytocompatibility In Vitro, and Anti-Bacterial Properties

He,

Liu,

Zeng

et al. 2023

JFB

View full text Add to dashboard Cite

show abstract

The Application Progress of Nonthermal Plasma Technology in the Modification of Bone Implant Materials

Ding,

Lv,

Huang

et al. 2024

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

With the accelerating trend of global aging, bone damage caused by orthopedic diseases, such as osteoporosis and fractures, has become a shared international event. Traffic accidents, high-altitude falls, and other incidents are increasing daily, and the demand for bone implant treatment is also growing. Although extensive research has been conducted in the past decade to develop medical implants for bone regeneration and healing of body tissues, due to their low biocompatibility, weak bone integration ability, and high postoperative infection rates, pure titanium alloys, such as Ti-6A1-4V and Ti-6A1-7Nb, although widely used in clinical practice, have poor induction of phosphate deposition and wear resistance, and Ti–Zr alloy exhibits a lack of mechanical stability and processing complexity. In contrast, the Ti–Ni alloy exhibits toxicity and low thermal conductivity. Nonthermal plasma (NTP) has aroused widespread interest in synthesizing and modifying implanted materials. More and more researchers are using plasma to modify target catalysts such as changing the dispersion of active sites, adjusting electronic properties, enhancing metal carrier interactions, and changing their morphology. NTP provides an alternative option for catalysts in the modification processes of oxidation, reduction, etching, coating, and doping, especially for materials that cannot tolerate thermodynamic or thermosensitive reactions. This review will focus on applying NTP technology in bone implant material modification and analyze the overall performance of three common types of bone implant materials, including metals, ceramics, and polymers. The challenges faced by NTP material modification are also discussed.

show abstract

Enhanced Bacteriostatic Properties of Ti Alloys by Surface Nitriding

Cited by 2 publications

References 31 publications

Silicon Nitride Bioceramics Sintered by Microwave Exhibit Excellent Mechanical Properties, Cytocompatibility In Vitro, and Anti-Bacterial Properties

Silicon Nitride Bioceramics Sintered by Microwave Exhibit Excellent Mechanical Properties, Cytocompatibility In Vitro, and Anti-Bacterial Properties

The Application Progress of Nonthermal Plasma Technology in the Modification of Bone Implant Materials

Contact Info

Product

Resources

About