Enhanced chemiluminescence for trazodone trace analysis based on acidic permanganate oxidation in concurrent presence of rhodamine 6G

Abstract

A new sensitized chemiluminescence method by acidic permanganate oxidation was developed for the sensitive determination of trazodone. A fluorescent dye as used rhodamine 6G to increase a chemiluminescence intensity. Under optimum conditions, the liner range of the calibration curve was obtained for 1-5000 nmol/L. The limit of detection was calculated from 3σ of a blank was 0.23 nmol/L. The coexistent ions and substances had no interference with the chemiluminescence measurement. The chemiluminescence spectra were measured to elucidate a possible mechanism for the system. The present method was satisfactorily used in the determination of the drugs in pharmaceutical samples and animal serums.

Chemiluminescence‐assisted study on a peracetic acid‐based advanced oxidation process activated with cobalt phosphide

“…Upon adding 2,4‐HD, RhB degradation was suppressed, which indicated that R–O• was also a contributor to RhB degradation (Figure 4e). CL emission was clearly affected by 2,4‐HD (Figure S9e), possibly because the intermediate formed by the oxidation of RhB by R–O• could promote CL in this system [37]. Mn 2+ has been reported to specifically eliminate CH 3 CO 3 • in PAA‐based AOPs [38].…”

“…NaN 3 was considered to be an effective scavenger of 1 O 2 [34]. In the presence of NaN 3 , the degradation efficiency and CL intensity sharply decreased along with an increase in NaN tem [37]. Mn 2+ has been reported to specifically eliminate CH 3 CO 3 • in PAA-based AOPs [38].…”

<p>Comparative study of β-cyclodextrin, γ-cyclodextrin and 4-<em>tert</em>-butylcalix[8]arene ionophores as electroactive materials for the construction of new sensors for trazodone based on host-guest recognition</p>

“…The importance of this drug in the treatment of such disorders and the severity of associated adverse effects renders its reliable determination very important. Different determination methods have been reported, including spectrophotometry2,7 spectrofluorometry,2,8 chemiluminescence,9 voltammetry,10–12 high-performance liquid chromatography (HPLC)- ultraviolet detection,13,14 HPLC-fluorescence1,15 and HPLC-mass spectroscopy (MS) 16. However, these techniques require expensive equipment, time-consuming methods and sometimes reproducibility and derivatization procedures.…”