Enhanced contrast radiography with channel-cut crystals at the LNLS

Hönnicke, Marcelo Gonçalves; Kellerman, G.; Rocha, H.S.; Giles, C.; Tirao, G.; Mazzaro, I.; Lopes, Ricardo Tadeu; Cusatis, C.

doi:10.1063/1.2018456

Cited by 6 publications

(3 citation statements)

References 31 publications

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“…The rocking curve of the analyzer crystal was considered as a Gaussian profile of width 12 mrad and the theoretical pixel size used was 10 mm Â 10 mm, approximately the spatial resolution of the acquired images. The same theoretical procedure has shown good agreement between the theoretical and experimental crosssectional profiles when applied to these samples using lower energies, a low-spatial-resolution CCD detector (22.5 mm Â 22.5 mm) and strain-free crystals (Hö nnicke et al, 2005). Also, these simulation procedures are similar to those used by Protopopov & Sobota (2002) using as analyzer a multilayer mirror with resonant absorption and conventional sources.…”

Section: Figurementioning

confidence: 66%

Quantitative and qualitative studies on high-contrast X-ray radiography with an asymmetrical crystal set-up at Elettra

Hönnicke

Rigon

Menk

et al. 2005

J Synchrotron Radiat

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An analyzer-based X-ray phase contrast imaging (ABI) system with an asymmetrical crystal set-up was mounted at Elettra's SYRMEP beamline. It was the first time that this set-up was implemented at Elettra. Advantages and disadvantages of such a set-up were exploited with quantitative and qualitative studies. For quantitative studies a simple hollow tube and strands were used as samples. Qualitative studies were developed using this technique with ox brain tissue, which has never been previously examined in this manner. Minute details were found in the ABIs and in the diffraction enhanced images. This could indicate the possibility of using these techniques with computerized tomography in the future as an auxiliary method in diagnosing brain illnesses such as Alzheimer and Creutzfeldt-Jacob disease. Propagation-based X-ray phase contrast imaging was also qualitatively exploited and compared with ABI using a Loxosceles gaucho spider as a sample.

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Section: Figurementioning

confidence: 66%

Quantitative and qualitative studies on high-contrast X-ray radiography with an asymmetrical crystal set-up at Elettra

Hönnicke

Rigon

Menk

et al. 2005

J Synchrotron Radiat

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“…1 ). Other phase contrast X-ray imaging experiments [ 27 , 28 ], including diffraction enhanced imaging [ 29 – 32 ] and PBI [ 9 , 30 ] had been already carried out at LNLS, however, in a diffraction beamline which does not have well prepared optical elements specially for imaging, like IMX has. The IMX beamline is a 20 m long beamline.…”

Section: Methodsmentioning

confidence: 99%

Are Human Peripheral Nerves Sensitive to X-Ray Imaging?

et al. 2015

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Diagnostic imaging techniques play an important role in assessing the exact location, cause, and extent of a nerve lesion, thus allowing clinicians to diagnose and manage more effectively a variety of pathological conditions, such as entrapment syndromes, traumatic injuries, and space-occupying lesions. Ultrasound and nuclear magnetic resonance imaging are becoming useful methods for this purpose, but they still lack spatial resolution. In this regard, recent phase contrast x-ray imaging experiments of peripheral nerve allowed the visualization of each nerve fiber surrounded by its myelin sheath as clearly as optical microscopy. In the present study, we attempted to produce high-resolution x-ray phase contrast images of a human sciatic nerve by using synchrotron radiation propagation-based imaging. The images showed high contrast and high spatial resolution, allowing clear identification of each fascicle structure and surrounding connective tissue. The outstanding result is the detection of such structures by phase contrast x-ray tomography of a thick human sciatic nerve section. This may further enable the identification of diverse pathological patterns, such as Wallerian degeneration, hypertrophic neuropathy, inflammatory infiltration, leprosy neuropathy and amyloid deposits. To the best of our knowledge, this is the first successful phase contrast x-ray imaging experiment of a human peripheral nerve sample. Our long-term goal is to develop peripheral nerve imaging methods that could supersede biopsy procedures.

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“…1, and characterized in details elsewhere [25]. The non-dispersive four-crystal ABI setup [26] consists of two symmetrical Si 333 channel-cuts, one as the first crystal positioned prior to the sample and the other as the analyzer crystal.…”

Section: Methodsmentioning

confidence: 99%