2024
DOI: 10.1002/edm2.515
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Enhanced Insulin Secretion Through Upregulation of Transcription Factors by Hydroalcoholic Extract of Securigera securidaca Seeds in Diabetic Animal Model

Maryam Hasani,
Ebrahim Abbasi‐Oshaghi,
Fatemeh Khomari
et al.

Abstract: AimIn previous studies, the researchers observed an increase in insulin secretion in STZ‐treated diabetic rats following treatment with the hydroalcoholic extract of Securigera securidaca (HESS) seeds. This study focuses on the relationship between the antioxidant properties of HESS with changes in diabetic pancreatic tissue and the gene expression of factors that impact insulin secretion.MethodsIn this controlled experimental study, three varying doses of HESS were administered to three groups of diabetic rat… Show more

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