Enhancement of Whitening Effects of Lithospermum erythrorhizon Extracts by Ultra High Pressure

Kim, Jinhyun; Jeong, Myoung-Hoon; Choi, Woon Yong; Seo, Yong-Chang; Ma, Choong-Je; Ahn, Juhee; Kim, Nam-Seong; Hwang, Baik; Cho, Jeong-Sub; Lee, Hyeon-Yong

doi:10.7783/kjmcs.2011.19.2.097

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…천연물은 다양한 연구에서 항산화 및 면역조절 기능을 나타 내는 것으로 보고되었으며, 이를 이용하여 피부에 자극이 적 은 반면 항노화, 미백, 주름개선 또는 항염증 등의 다양한 기 능성을 갖는 한방화장품을 개발하기 위한 연구들이 주목받고 있다 Kim et al, 2011;Lee et al, 2011;Seo et al, 2009). 특히, 최근 항산화 효과 및 면역조절 작용 등을 나타내는 천연물을 이용하여 발모효과가 우수하면서도 부작용이 적은 발모제를 개발하기 위한 연구들이 다양하게 수 행되고 있다.…”

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The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion

Kim¹,

Hong²,

Hwang³

et al. 2012

Korean Journal of Medicinal Crop Science

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: In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing Rosa multiflora roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP (125.0 ± 4.9 FU/㎠) compared to before treatment (104.3 ± 4.7 FU/㎠, p < 0.05), and hair thickness were also significantly increased (0.066 ± 0.003 ㎜) than before treatment (0.055 ± 0.002 ㎜, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with 1.23 ± 0.05 (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

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The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion

Kim¹,

Hong²,

Hwang³

et al. 2012

Korean Journal of Medicinal Crop Science

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Identification of Fungal Pathogen Causing Seedling Rot of Lithospermum erythrorhizon and Study on the Optimum Growing Temperature for Decreasing of the Seedling Rot

An¹,

Shin²,

Ahn³

et al. 2013

Korean Journal of Medicinal Crop Science

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: This study was conducted to isolate and identify the fungal pathogen causing seedling rot of Lithospermum erythrorhizon Siebold & Zuccarini, and to know the optimum growing temperature for decreasing seedling rot of Lithospermum erythrorhizon. On the basis of morphological characteristics, EF-1a sequence analysis, and pathogenecity to host plant, the fungi isolated from seedling rot and seeds of Lithospermum erythrorhizon were identified as Fusarium fujikuroi, indicating that disease causing fungus is seed-borne pathogen. Optimum temperature for germination of seeds of Lithospermum erythrorhizon was 15~20℃, but pathogenicity of Fusarium fujikuroi was shown more readily at 25~30℃. These results suggested that seedling culture of Lithospermum erythrorhizon between 15℃ and 20℃ might reduce seedling rot of Lithospermum erythrorhizon caused by seed-borne pathogen Fusarium fujikuroi.

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Enhancement of Whitening Effects of Lithospermum erythrorhizon Extracts by Ultra High Pressure

Cited by 2 publications

References 6 publications

The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion

The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion

Identification of Fungal Pathogen Causing Seedling Rot of Lithospermum erythrorhizon and Study on the Optimum Growing Temperature for Decreasing of the Seedling Rot

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