Enhancing Host Resistance to Pressure Ulcers: A New Approach to Prevention

Mawson, Anthony R.; Siddiqui, F.; Biundo, Joseph J.

doi:10.1006/pmed.1993.1036

Cited by 24 publications

(10 citation statements)

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“…Both low resting systolic pressure 145 and immobility leading to sustained external pressure 146 produce local skin ischemia in patients at risk for pressure ulcers (i.e., the elderly and persons recovering from spinal cord injury 147 ). Loss of vasomotor control also contributes to poor perfusion 148 . Pressure ulcers have been treated successfully in randomized trials with the use of topically applied bFGF 149,150 .…”

Section: Pressure Ulcersmentioning

confidence: 99%

The Role of Vascular Endothelial Growth Factor in Wound Healing

Bao

Kodra

Tomic‐Canic

et al. 2009

Journal of Surgical Research

964

732

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Section: Pressure Ulcersmentioning

confidence: 99%

The Role of Vascular Endothelial Growth Factor in Wound Healing

Bao

Kodra

Tomic‐Canic

et al. 2009

Journal of Surgical Research

964

732

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“…It has been proposed that high voltage pulsed galvanic stimulation (HVPGS) restores sympathetic tone and vascular resistance below the level of the spinal cord lesion, and thereby may increase the perfusion pressure gradient in the capillary beds [127]. HVPGS has been shown to induce a 35% increase in sacral PtcO 2 , from a baseline level of 49 mmHg to 66 mmHg after 30 minutes of stimulation on subjects lying supine [128].…”

Section: Electrical Stimulationmentioning

confidence: 99%

“…High-voltage pulsed galvanic stimulation (75 V, 10 Hz) applied to the back at spinal level T6 in spinalcord-injured persons lying supine raises sacral transcutaneous oxygen tension levels to the normal ranges [128]. Thus, high-voltage pulsed galvanic stimulation may be instrumental in preventing pressure ulcers in spinal-cordinjured persons and other groups at high risk [127]. Although both increase cutaneous blood flow, and promote the healing of pressure ulcers, there is no literature on the influences of using negative pressure and electrical stimulation parallel [129].…”

Section: Negative Pressure and Electrical Stimulationmentioning

confidence: 99%

Techniques for Wound Healing with a Focus on Pressure Ulcers Elimination

Kuffler¹

2012

TOCVJ

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Pressure ulcers, also called decubitus ulcers, are a common challenge of humanity. They are wounds initiated by pressure on the skin that blocks circulation causing the skin and underlying tissues to die. Without care, pressure ulcers continue to grow in diameter and depth and are exceptionally difficult to heal. They have probably always existed, and are present on Egyptian mummies. Pressure ulcers are a serious health issue, very painful, a significant physiological challenge, can shorten the life of a patient, are an emotional and financial burden to the patient, those who deal with them, and in the United States alone annually costs in excess over $10 billion dollars for care and prolonged hospitalization. Pressure ulcers can develop with as little as two hours of pressure, and because even a brief lapse in avoidance of pressure leads to ulcers, they are frequently impossible to prevent, even for the most conscientious patient with an extensive support group and unlimited financial resources. Therefore, enormous effort is required to find effective and reliable techniques for preventing the initiation of ulcers and eliminating them once they develop. This review looks at the various approaches presently used and in development for the treatment of pressure ulcers, evaluates which may be best in eliminating ulcers, and discusses combinations of techniques that may be most effective in eliminating pressure ulcers.

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“…24 Literature about high-voltage pulsed galvanic stimulation (HVPGS) is usually about its effects on force of induced muscle contraction, augmentation of muscle strength, muscle blood flow, reduction of pain and discomfort in patients with levator ani syndrome, and healing of thermal burns and dermal ulcers. [25][26][27][28][29][30] We did not find any study in the literature regarding its usage in patients with FM.…”

mentioning

confidence: 99%