Enhancing Proton Therapy Efficacy Through Nanoparticle-Mediated Radiosensitization
Jie Ma,
Hao Shen,
Zhaohong Mi
Abstract:Proton therapy, characterized by its unique Bragg peak, offers the potential to optimize the destruction of cancer cells while sparing healthy tissues, positioning it as one of the most advanced cancer treatment modalities currently available. However, in comparison to heavy ions, protons exhibit a relatively lower relative biological effectiveness (RBE), which limits the efficacy of proton therapy. The incorporation of nanoparticles for radiosensitization presents a novel approach to enhance the RBE of proton… Show more
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