Enquête sur la mise en place d’une consultation pharmaceutique pour les patients sous antirétroviraux

Guerrault, Marie-Noëlle; Leclerc, C.; Langevin, Stéphan; Merian-Brosse, L; Brossard, Denis; Welker, Yves

doi:10.1016/s0755-4982(05)84226-5

Cited by 7 publications

(3 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The roles include medication monitoring, management of drug-related adverse events and adherence counselling [ 24 – 29 ] Indeed, pharmacists 1) are uniquely-placed to provide patients with individualized education and 2) have vital roles in improving ART adherence [ 28 , 30 ]. People living with HIV who receives pharmaceutical education believe that it is beneficial, particularly for managing drug interactions, side effects and missed doses [ 31 ]. The notion is supported by existing systematic review of randomized and non-randomized controlled trials, pre-post comparisons and cohort studies, which indeed confirmed a positive association between pharmacist-led interventions and ART adherence [ 32 ].…”

Section: Introductionmentioning

confidence: 99%

Pharmacist-led counselling intervention to improve antiretroviral drug adherence in Pakistan: a randomized controlled trial

et al. 2020

View full text Add to dashboard Cite

Background Pakistan is facing a growing population of people living with human immunodeficiency (HIV). In this randomized controlled trial, we investigate if a pharmacist-led intervention can increase adherence to antiretroviral therapy (ART) for people living with HIV (PLWH). Methods Adults with HIV, who have been taking ART for more than 3 months were randomly assigned to receive either a pharmacist-led intervention or their usual care. Measures of adherence were collected at 1) baseline 2) just prior to delivery of intervention and 3) 8 weeks later. The primary outcomes were CD4 cell count and self-reported adherence measured with the AIDS Clinical Trial Group (ACTG) questionnaire. Results Post-intervention, the intervention group showed a statistically significant increase in CD4 cell counts as compared to the usual care group (p = 0.0054). In addition, adherence improved in the intervention group, with participants being 5.96 times more likely to report having not missed their medication for longer periods of time (p = 0.0086) while participants in the intervention group were 7.74 times more likely to report missing their ART less frequently (p < 0.0001). Conclusions The findings support the improvement in ART adherence and HIV management. Trial registration The trial is registered with Australian New Zealand Clinical Trials Registry (ACTRN12618001882213). Registered 20 November 2018.

show abstract

Section: Introductionmentioning

confidence: 99%

Pharmacist-led counselling intervention to improve antiretroviral drug adherence in Pakistan: a randomized controlled trial

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In a survey of persons with HIV, 72% said they would find a pharmacy consultation useful. 24 Furthermore, respondents requested more practitioner-patient engagement in the areas of drug interaction screening, side effects management, and proper dosing instructionsall factors specific to pharmacy scope of practice and services. 24 Pharmacists have become keys players in targeting adherence improvement within the HIV population.…”

Section: Introductionmentioning

confidence: 99%

“…24 Furthermore, respondents requested more practitioner-patient engagement in the areas of drug interaction screening, side effects management, and proper dosing instructionsall factors specific to pharmacy scope of practice and services. 24 Pharmacists have become keys players in targeting adherence improvement within the HIV population. 25 A review of three pharmacy-driven adherence clinics showed that the inclusion of pharmacist education and counseling resulted in statistically higher adherence rates in all studies compared to control groups.…”

Section: Introductionmentioning

confidence: 99%

Assessing the Effectiveness of Pharmacy-Based Adherence Interventions on Antiretroviral Adherence in Persons with HIV

Henderson

Hindman

Johnson

et al. 2011

AIDS Patient Care and STDs

View full text Add to dashboard Cite

A key factor to the successful treatment of HIV is good adherence to antiretroviral therapy (ART). We developed a pharmacist-managed adherence clinic and designed a study to assess the impact of the adherence interventions by measuring the proportion of patients with 95% or greater adherence to ART before and after referral to the program. HIV providers referred patients with adherence problems to a pharmacist-managed adherence clinic. Interventions included scheduled clinic visits with the HIV Clinical Pharmacist and monthly refill reminders from pharmacy staff members over a 6-month period. Those aged 18-75, prescribed an ART regimen for a minimum of 3 months, and who filled their medications exclusively at the clinic pharmacy were eligible for study participation. The Proportion of Days Covered (PDC) served as a surrogate marker of overall adherence. A total of 34 patients were referred to the pharmacy clinic for adherence counseling, of whom 28 enrolled in the study. The proportion of participants with 95% or greater adherence to their ART regimen increased from 7% at baseline to 32% postintervention (p = 0.01). A subanalysis of the PDC revealed an overall increase from a baseline adherence mean of 60% to 81% postintervention (p < 0.0001). There was a notable trend toward an increase in the proportion of participants with an undetectable HIV-1 viral load (58-73%, baseline and postintervention, respectively, p = 0.10), but no statistically significant improvement in CD4 cell count. Clinical pharmacy interventions improved overall adherence to ART regimens in these patients with HIV.

show abstract

Mise à jour des activités pharmaceutiques dans une clinique ambulatoire de VIH/SIDA pédiatrique

Stöckel

Bédard

Métras

et al. 2015

Le Pharmacien Hospitalier et Clinicien

View full text Add to dashboard Cite

Enquête sur la mise en place d’une consultation pharmaceutique pour les patients sous antirétroviraux

Cited by 7 publications

References 6 publications

Pharmacist-led counselling intervention to improve antiretroviral drug adherence in Pakistan: a randomized controlled trial

Pharmacist-led counselling intervention to improve antiretroviral drug adherence in Pakistan: a randomized controlled trial

Assessing the Effectiveness of Pharmacy-Based Adherence Interventions on Antiretroviral Adherence in Persons with HIV

Mise à jour des activités pharmaceutiques dans une clinique ambulatoire de VIH/SIDA pédiatrique

Contact Info

Product

Resources

About