Enterococcal bacteraemia: Epidemiological, microbiological, clinical and prognostic characteristics, and the impact of high level gentamicin resistance

Shaked, Hila; Carmeli, Yehuda; Schwartz, David; Siegman-Igra, Yardena

doi:10.1080/00365540600868321

Cited by 30 publications

(37 citation statements)

References 17 publications

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“…Çalışmamızda enterokok bakteriyemilerinin 56 (%59)'sı monomikrobiyal ve 39 (%41)'u polimikrobiyal bakteriyemiy- Kaynağı saptanabilen enterokok bakteriyemilerinde, en sık kaynak (%19-43) üriner sistemdir (9,11,17). Enterokok bakteriyemilerinin en sık kaynağı, Jang ve arkadaşları (18) tarafından safra yolu infeksiyonu; Conde-Estévez ve arkadaşları (19) ile Tan ve arkadaşları (20) tarafından ise santral venöz katetere bağlı kan dolaşımı infeksiyonu olarak saptanmıştır.…”

Section: İrdelemeunclassified

“…Enterokok bakteriyemilerinin %60-78'i nozokomiyaldir ve bu infeksiyonların yarısı yoğun bakım ünitelerinde görülmek-tedir (11,12,21 mızda kan kültüründe üreyen iki enterokok kökeninde vankomisin direnci saptadık. Bu enterokok kökenlerinin, biri E. faecalis (vanA tipi direnç) ve diğeri E. gallinarum (vanC tipi direnç) idi.…”

Section: İrdelemeunclassified

“…Antibiyotik kullanım öyküsünün, özellikle antianaerop etkinliği olan antibiyotikler, sefolosporinler, aminoglikozidler, imipenem ve siprofloksasin kullanımının, enterokok bakteriyemisi gelişiminde iyi tanımlanmış bir risk faktörü olduğu bildirilmektedir (9)(10)(11)(12). Olgu grubumuzda antibiyotik kullanım süresi (8.0±3.8 gün), kontrol grubundan anlamlı olarak (p<0.001) daha uzundu.…”

Section: İrdelemeunclassified

“…Enterokoklar çoğunlukla sol kalp endokarditine neden olur ve mitral kapak, aort kapağına göre daha sık tutulur. Enterokok endokarditlerinde sıklıkla E. faecalis etkendir (10)(11)(12). Ça-lışmamızda altı olguda (%6.3) enterokok endokarditi saptandı.…”

Section: İrdelemeunclassified

“…Enterokok menenjiti daha çok kafa travması, beyin cerrahisi girişimleri sonrası veya santral sinir sisteminde anatomik defekti olan hastalarda görülür (9)(10)(11)(12). Çalışmamızda iki olguda (%2.1) enterokok menenjiti görüldü.…”

Section: İrdelemeunclassified

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Evaluation of Risk Factors in Enterococcal Bloodstream Infections

Alkan¹,

Kuloğlu²,

Akata³

2016

Klimik Dergisi

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Objective: The aim of this retrospective case-control study was to determine the epidemiology and to evaluate risk factors for the development of enterococcal bloodstream infections and risk factors involved in mortality of adult patients in a tertiary care teaching hospital between February 2010 and February 2011. Methods: A total of 95 enterococcal bacteremia episodes were identified among 28 593 patients hospitalized during the study period. Control group was selected among patients who had no signs and symptoms of bacteremia and had negative blood cultures during the study period. In each case, there had to be two randomized control cases. Results:The most frequent isolates were Enterococcus faecalis (n=46, 48.4%) and E. faecium (n=45, 47.4%). There was only one vancomycin-resistant E. faecalis (vanA genotype) and one E. gallinarum. Eighty four (88.4%) patients were identified to have nosocomial infection. The most common primary sites were central venous catheter (32.7%) and urinary tract (14.7%). Six cases of infective endocarditis and two cases of meningitis due to enterococci were also identified. Polymicrobial bacteremia occurred in 39 (41%) patients. Immunosuppression, cardiovascular disease, chronic liver parenchymal disease, gastrointestinal tract disease, chronic renal failure, hemodialysis, an open wound, Foley catheter, surgery other than abdominal operation, antacid use, hospitalization in the last one month, prolonged hospitalization (>15 days), exposure to antimicrobial therapy prior to bacteremia and inappropriate empirical therapy were the risk factors significantly associated with enterococcal bloodstream infections. In the multivariate logistic regression analysis, three factors were independently associated with mortality including high Charlson index (p=0.000), intensive care unit admission (p=0.016) and isolation of E. faecium from blood cultures (p=0.49). Conclusions: It should be considered that severely ill patients with prolonged hospitalization, those undergoing invasive procedures or receiving inappropriate antibiotic therapy have a high risk of enterococcal bacteremia and those with serious underlying comorbidities are likely to be unresponsive to treatment and have a higher mortality. gallinarum).Olguların 84 (%88.4)'ünde hastane kökenli bakteriyemi saptandı. En sık primer infeksiyon kaynağı santral venöz kateter (%32.7) ve üriner sistem (%14.7) idi. Altı hastada bakteriyemiye eşlik eden infektif endokardit, iki hastada menenjit saptandı. Enterokok bakteriyemilerinin 39 (%41)'u polimikrobiyal bakteriyemiydi. İmmünosüpresyon, kardiyovasküler sistem hastalığı, kronik karaciğer parenkim hastalığı, gastrointestinal sistem hastalıkları, kronik böbrek yetmezliği, diyaliz tedavisi, açık yara, Foley sondası, abdominal cerrahi dışındaki cerrahi girişim, antasid kullanımı, son bir aylık dönemde hastanede yatış, hastanede yatış süresinin 15 günden fazla olması, bakteriyemi öncesi antibiyotik kullanımı ve uygun olmayan ampirik antibiyotik tedavisi, olgu grubunda anlamlı olarak daha...

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Section: İrdelemeunclassified

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Evaluation of Risk Factors in Enterococcal Bloodstream Infections

Alkan¹,

Kuloğlu²,

Akata³

2016

Klimik Dergisi

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Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat

Colella,

Greco,

Cordisco

et al. 2023

Vet Record Case Reports

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Feline infective endocarditis is a difficult condition to detect and diagnose early, with a poor long‐term prognosis. This case report describes the clinical, laboratory, instrumental and histological findings in a 12‐year‐old cat with Bartonella henselae endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia. The latter pathogen recently emerged as deadly nosocomial bacteria in humans and is considered a common cause of infective endocarditis. The prolonged corticosteroid therapy administered in the cat probably played a role in the onset of B. henselae endocarditis and E. faecalis intestinal translocation and bacteraemia. Echocardiography remains the tool of choice to suspect infective endocarditis, as it can detect vegetative lesions consistent with this condition. Feline infective endocarditis should always be considered as a differential diagnosis in cats, especially when there are signs of systemic disease, a history of prolonged corticosteroid treatment or concomitant infections.

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Hygienemaßnahmen zur Prävention der Infektion durch Enterokokken mit speziellen Antibiotikaresistenzen

Krinko¹

2018

Bundesgesundheitsbl

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Enterococcal bacteraemia: Epidemiological, microbiological, clinical and prognostic characteristics, and the impact of high level gentamicin resistance

Cited by 30 publications

References 17 publications

Evaluation of Risk Factors in Enterococcal Bloodstream Infections

Evaluation of Risk Factors in Enterococcal Bloodstream Infections

Bartonella henselae mitral valve endocarditis associated with multi‐resistant Enterococcus faecalis bacteraemia in a cat

Hygienemaßnahmen zur Prävention der Infektion durch Enterokokken mit speziellen Antibiotikaresistenzen

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