Cloud computing is considered the next step in the evolution of technological applications, services and products development, in the Future Internet and Internet of Things context. The permanent connection of users to the Internet has become widespread, so almost all available resources (data, software) can be placed on the Internet, shared between users - sometimes completely independently of others, and brought from the Internet to the user's computer on demand. The chapter highlights the benefits of using hybrid technology with a focus towards entrepreneurs and business innovators. Intercloud systems are built of heterogeneous services, offered by different providers of cloud computing. To emphasize the business opportunities offered by innovative Intercloud approaches, an architecture for the interconnection of cloud services offered by multiple cloud providers, with applications to e-health, is presented. The main concepts and business benefits of using Intercloud systems and an architecture for interconnecting cloud services from multiple cloud providers is described.