Stressors and demands related to changes in work environment may result in impairments of employees' health and ability to work. In the context of the German statutory pension insurance's inpatient medical rehabilitation, these aspects are increasingly taken into account within the concept of vocationally oriented medical rehabilitation (VOMR). Nonetheless, a comprehensive implementation of diagnostic and therapeutic concepts in rehabilitative practice has not yet been realized. In this article, a profile of requirements for VOMR which has been developed by the German pension insurance is introduced that shall contribute to aligning rehabilitative measures for patients with work-related problems with occupational demands. Moreover, approaches for implementing vocationally oriented measures in diagnostics (e.g., screenings) and therapy (e.g., job training) as well as good practice examples are presented. In addition, user-oriented media (handbook, homepage) which enable researchers and clinicians to learn about the current state of research in this area are highlighted. Starting points for further development of vocational orientation in rehabilitation are discussed.