Environmental Modifications for Controlling Acute Respiratory Disease1

Lehane, Daniel E.; Newberg, Neil R.; Beam, Walter E.

doi:10.1093/oxfordjournals.aje.a121594

Cited by 8 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11 Environmental controls, such as germicidal sprays and ultraviolet light sterilization, have failed. 12,13 Hand washing has had only anecdotal success. Cohorting, maintaining recruits in separate training groups with minimal interaction, has been partially successful; however, it may only delay adenovirus-ARD until later stages of training.…”

Section: Introductionmentioning

confidence: 99%

Cost-effectiveness analysis of reacquiring and using adenovirus types 4 and 7 vaccines in naval recruits.

Hyer¹,

Howell²,

Ryan³

et al. 2000

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Adenovirus vaccines have controlled acute respiratory disease (ARD) in military recruits since 1971. Vaccine production, however, ceased and new facilities are required. We assessed whether reacquiring and using vaccines in naval recruits is cost-effective. Three policy options were evaluated: no vaccination, seasonal vaccination, and year-round vaccination. Morbidity (outpatient and inpatient), illness costs (medical and lost training), and vaccine program costs (start-up, acquisition, and distribution) were modeled using a decision-analytic method. Results were based on a cohort of 49,079 annual trainees, a winter vaccine-preventable ARD rate of 2.6 cases per 100 personweeks, a summer incidence rate at 10% of the winter rate, a hospitalization rate of 7.6%, and a production facility costing US$12 million. Compared to no vaccination, seasonal vaccination prevented 4,015 cases and saved $2.8 million per year. Year-round vaccination prevented 4,555 cases and saved $2.6 million. Reacquiring and using adenovirus vaccines seasonally or year-round saves money and averts suffering.

show abstract

Section: Introductionmentioning

confidence: 99%