Environmental temperature variation affects brain protein expression and cognitive abilities in adult zebrafish (Danio rerio): A proteomic and behavioural study

Toni, Mattia; Angiulli, Elisa; Miccoli, G.; Cioni, Carla; Alleva, Enrico; Frabetti, Flavia; Pizzetti, Fabrizio; Scalvini, Francesca Grassi; Nonnis, Simona; Negri, Armando; Tedeschi, Gioacchino; Maffioli, Elisa

doi:10.1016/j.jprot.2019.103396

Cited by 51 publications

(92 citation statements)

References 86 publications

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“…Data collected in the present study demonstrate that adaptation for 21 days at 34 °C caused an impairment of natural zebrafish behaviour and corroborates previous results that showed how the same heat treatment can alter the expression of brain proteins that are involved in important cellular events such as synaptic plasticity and neurotransmitter release, thereby altering zebrafish cognitive abilities 8 . This suggests that the behavioural alteration induced by heat treatment may be a consequence of neurochemical alterations.…”

Section: Discussionsupporting

confidence: 92%

“…Fish husbandry during adaptation and thermal treatment. Zebrafish husbandry was based on the same protocol used previously 8 , and all procedures were conducted in the same laboratory room using the same home tanks and housing conditions previously described. Briefly, two identical glass home tanks (width (W) 40 x depth (D) 30 x height (H) 30 cm) were used.…”

Section: Subjectsmentioning

confidence: 99%

“…To minimize the interference between the different tests 31,32 , the NTT and LDT were performed alternately as the first or second test, whereas the SPT and MBT were performed alternately as the third or fourth test. Each individual zebrafish was captured by using a beaker and transferred from the home tank to the waiting tank (W15 x D10 x H10 cm) for 30 min until the beginning of the behavioural test 8 . The temperature of the water in all the tanks used in the behavioural tests was the same as the home tank in which the animal had been housed and was held constant at 26 °C or 34 °C with a maximum variation of 1 °C between the beginning and the end of each test.…”

Section: Subjectsmentioning

confidence: 99%

“…Temperature has been defined as the "abiotic master factor" for fish 2 because it is one of the most important water parameters that affects fish biology, and for this reason, it must be considered in research and aquaculture to ensure animal welfare 3,4 . Variations in environmental temperature strongly affect fish biology not only by influencing growth, reproduction, spontaneous activity and metabolism 5 , as is well known for ectothermic animals, but also by affecting neurochemical parameters and behaviour [6][7][8] .…”

mentioning

confidence: 99%

“…With the aim of investigating the impact of thermal variation on the nervous system and zebrafish behaviour, we have recently analysed the effects of temperature on the brain proteome of adult zebrafish exposed for 21 days to low (18 °C) and high (34 °C) temperatures and provided evidence that the thermal treatment up-or downregulates the expression of proteins involved in cytoskeletal organization, mitochondrial regulation, energy metabolism and synaptic functioning in the central nervous system (CNS) 8 . Behavioural tests performed in the same study using a Y-Maze apparatus also revealed significant alterations in zebrafish behaviour that could be related to the impairment of specific cognitive abilities caused by thermal treatment 8 .…”

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confidence: 99%

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Increase in environmental temperature affects exploratory behaviour, anxiety and social preference in Danio rerio

Angiulli¹,

Pagliara²,

Cioni³

et al. 2020

Sci Rep

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The aim of this work is to investigate the effect of a temperature increase on the behaviour of adult zebrafish (Danio rerio) maintained for 21 days at 34 °C (treatment) and 26 °C (control). The temperatures chosen are within the vital range of zebrafish and correspond to temperatures that this species encounters in the natural environment. Previous results showed that the same treatment affects the brain proteome and the behaviour of adult zebrafish by producing alterations in the proteins involved in neurotransmitter release and synaptic function and impairing fish exploratory behaviour. In this study, we have investigated the performance of treated and control zebrafish during environmental exploration by using four behavioural tests (novel tank diving, light and dark preference, social preference and mirror biting) that are paradigms for assessing the state of anxiety, boldness, social preference and aggressive behaviour, respectively. The results showed that heat treatment reduces anxiety and increases the boldness of zebrafish, which spent more time in potentially dangerous areas of the tank such as the top and the uncovered bright area and at a distance from the social group, thus decreasing protection for the zebrafish. These data suggest that the increase in ambient temperature may compromise zebrafish survival rate in the natural environment.

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Section: Discussionsupporting

confidence: 92%

Section: Subjectsmentioning

confidence: 99%

Section: Subjectsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Increase in environmental temperature affects exploratory behaviour, anxiety and social preference in Danio rerio

Angiulli¹,

Pagliara²,

Cioni³

et al. 2020

Sci Rep

Self Cite

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The impacts of heat stress on animal cognition: Implications for adaptation to a changing climate

Soravia

Ashton

Thornton

et al. 2021

WIREs Climate Change

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With global surface air temperature rising rapidly, extensive research effort has been dedicated to assessing the consequences of this change for wildlife. While impacts on the phenology, distribution, and demography of wild animal populations are well documented, the impact of increasing temperature on cognition in these populations has received relatively little attention. Cognition encompasses the mental mechanisms that allow individuals to process information from the surrounding environment, respond accordingly, and flexibly adjust behavior. Hence, it is likely to be a key factor in allowing animals to adjust adaptively to climate change. Captive studies show that heat stress can negatively affect cognitive performance not only in the short‐term but also in the long‐term, by altering cognitive development at early life stages. Field studies indicate that cognitive performance may affect survival and reproductive success. However, the link between heat stress, cognition, and fitness in wild animals has yet to be formally established. We propose a comprehensive research framework for the collection of robust empirical datasets on heat stress and cognitive performance in the wild. We then suggest how knowledge of heat stress impacts on cognitive performance could be applied to population viability models and wildlife management actions. We believe that a joint research effort encompassing the fields of thermal physiology, behavioral ecology, comparative cognition, and conservation science, is essential to provide timely mitigation measures against the potential impacts of climate change on wildlife. This article is categorized under: Climate, Ecology, and Conservation > Observed Ecological Changes

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Pikeperch (Sander lucioperca) adaptive or maladaptive reactions to environmental stressors؟ a review

Pourhosein-Sarameh,

Falahatkar

2024

Aquacult Int

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Environmental temperature variation affects brain protein expression and cognitive abilities in adult zebrafish (Danio rerio): A proteomic and behavioural study

Abstract: Environmental temperature variation affects brain protein expression and cognitive abilities in adult zebrafish (Danio rerio): a proteomic and behavioural study M. Toni 1,*

Cited by 51 publications

References 86 publications

Increase in environmental temperature affects exploratory behaviour, anxiety and social preference in Danio rerio

Increase in environmental temperature affects exploratory behaviour, anxiety and social preference in Danio rerio

The impacts of heat stress on animal cognition: Implications for adaptation to a changing climate

Pikeperch (Sander lucioperca) adaptive or maladaptive reactions to environmental stressors؟ a review

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