Enzymes in Polymers and Polymers from Enzymes

Kline, Billie J.; Drevon, Géraldine F.; Russell, Alan J.

doi:10.1007/978-94-010-0924-9_20

Cited by 2 publications

(1 citation statement)

References 118 publications

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“…Recent advances in materials synthesis using enzymes have allowed the preparation of a variety of bioplastics and enzyme-polymer composites for use as reactive monoliths, foams, fibers, wipes, and coatings (122)(123)(124). These polymers involve the incorporation (usually covalent) of the biological material directly into the polymer.…”

Section: Biomaterials Against Chemical Weaponsmentioning

confidence: 99%

Biomaterials for Mediation of Chemical and Biological Warfare Agents

Russell

Berberich²,

Drevon³

et al. 2003

Annu. Rev. Biomed. Eng.

187

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Recent events have emphasized the threat from chemical and biological warfare agents. Within the efforts to counter this threat, the biocatalytic destruction and sensing of chemical and biological weapons has become an important area of focus. The specificity and high catalytic rates of biological catalysts make them appropriate for decommissioning nerve agent stockpiles, counteracting nerve agent attacks, and remediation of organophosphate spills. A number of materials have been prepared containing enzymes for the destruction of and protection against organophosphate nerve agents and biological warfare agents. This review discusses the major chemical and biological warfare agents, decontamination methods, and biomaterials that have potential for the preparation of decontamination wipes, gas filters, column packings, protective wear, and self-decontaminating paints and coatings.

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Section: Biomaterials Against Chemical Weaponsmentioning

confidence: 99%

Biomaterials for Mediation of Chemical and Biological Warfare Agents

Russell

Berberich²,

Drevon³

et al. 2003

Annu. Rev. Biomed. Eng.

187

View full text Add to dashboard Cite

show abstract

Catalyst Deactivation/Regeneration – Biological

Drevon

Russell

2002

Encyclopedia of Catalysis

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Biocatalyst inactivation is caused by external stresses, including high pressures and temperatures, extreme pH's, organic media, freezing, drying, and oxidative, chelating, and denaturing agents. These stresses may result either in reversible or irreversible activity loss. The main structural and covalent mechanisms in biocatalyst inactivation such as the disulfide intra‐ and interexchanges, the deamidation of asparagine residues, the decomposition of disulfide bridges by β‐elimination, the hydrolysis of peptide chains, the β‐isomerization of asparagine and aspartic acid residues, and amino acid racemization are discussed. The strategies that have been developed to prevent biocatalyst inactivation, i.e. chemical modification immobilization, protein engineering, directed evolution, are briefly presented.

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Enzymes in Polymers and Polymers from Enzymes

Cited by 2 publications

References 118 publications

Biomaterials for Mediation of Chemical and Biological Warfare Agents

Biomaterials for Mediation of Chemical and Biological Warfare Agents

Catalyst Deactivation/Regeneration – Biological

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