EP-1113: Light seeing in radiotherapy of patients with brain tumours and head and neck malignancies

Farzin, Mostafa; Molls, M.; Astner, Sabrina T.; Reitz, Silvia; Kreiser, Kornelia; Kampfer, S.

doi:10.1016/s0167-8140(16)32363-5

Cited by 2 publications

(2 citation statements)

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“…In the course of RT, Cherenkov radiation (CR) energy was produced in the eyes and may be helpful in inducing VLPs [ 33 ]. The CR produced by eyeballs may be the origin of VLPs in patients with head and neck cancer treated by RT [ 34 ]. During PT, 60% of the subjects experienced VLPs, among which 74% saw a blue light.…”

Section: Discussionmentioning

confidence: 99%

Visual light perceptions caused by medical linear accelerator: Findings of machine-learning algorithms in a prospective questionnaire-based case–control study

Kuo

Lee

et al. 2021

PLoS ONE

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This study aimed to investigate the possible incidence of visual light perceptions (VLPs) during radiation therapy (RT). We analyzed whether VLPs could be affected by differences in the radiation energy, prescription doses, age, sex, or RT locations, and whether all VLPs were caused by radiation. From November 2016 to August 2018, a total of 101 patients who underwent head-and-neck or brain RT were screened. After receiving RT, questionnaires were completed, and the subjects were interviewed. Random forests (RF), a tree-based machine learning algorithm, and logistic regression (LR) analyses were compared by the area under the curve (AUC), and the algorithm that achieved the highest AUC was selected. The dataset sample was based on treatment with non-human units, and a total of 293 treatment fields from 78 patients were analyzed. VLPs were detected only in 122 of the 293 exposure portals (40.16%). The dataset was randomly divided into 80% and 20% as the training set and test set, respectively. In the test set, RF achieved an AUC of 0.888, whereas LR achieved an AUC of 0.773. In this study, the retina fraction dose was the most important continuous variable and had a positive effect on VLP. Age was the most important categorical variable. In conclusion, the visual light perception phenomenon by the human body during RT is induced by radiation rather than being a self-suggested hallucination or induced by phosphenes.

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Section: Discussionmentioning

confidence: 99%

Visual light perceptions caused by medical linear accelerator: Findings of machine-learning algorithms in a prospective questionnaire-based case–control study

Kuo

Lee

et al. 2021

PLoS ONE

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“…In these cases the most important key parameters were linked to tumor location and dose. For the detailed considerations related to these the reader is addressed to the original papers (see also [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] ). Most of the studies were prospective studies where the patient was aware of the study, and accepted it before the therapy, and was asked questions about the illusions immediately after each therapy session.…”

Section: Proton/hadron-therapy a New Channel To Study Lfmentioning

confidence: 99%

Light flashes and other sensory illusions perceived in space travel and on ground, including proton and heavy ion therapies

Narici

2024

Zeitschrift für Medizinische Physik

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EP-1113: Light seeing in radiotherapy of patients with brain tumours and head and neck malignancies

Cited by 2 publications

References 0 publications

Visual light perceptions caused by medical linear accelerator: Findings of machine-learning algorithms in a prospective questionnaire-based case–control study

Visual light perceptions caused by medical linear accelerator: Findings of machine-learning algorithms in a prospective questionnaire-based case–control study

Light flashes and other sensory illusions perceived in space travel and on ground, including proton and heavy ion therapies

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