Epidemiological and clinical profile, management and outcomes of young patients (≤40 years) with acute coronary syndrome: A single tertiary care center study

Revaiah, Pruthvi C; Santosh, Krishna; Vijayvergiya, Rajesh; Bahl, Ajay; Gupta, Ankur; Bootla, Dinakar; Kasinadhuni, Ganesh; Prasad, Krishna; Rajan, Manu; Uppal, Lipi; Gawalkar, Atit A; Rohit, Manoj Kumar

doi:10.1016/j.ihj.2021.01.015

Cited by 21 publications

(11 citation statements)

References 30 publications

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“…As per studies by Sharma and his fellows the chest pain was reported in patients that had average age 35-45 years and among them there were 68% male. In our study it was found that the incidence or occurrence of hypertension in the participants with chest pain was 37%, with 236% patients reported about diabetes and 23% of them were smokers [15][16] . As per studies by Gandhi and his fellows it was found that among the patients that reported chest pain at the tertiary care center, 61% of them had hypertension and 30% of them had diabetes mellitus.…”

Section: Discussionmentioning

confidence: 53%

Estimation of Prevalence Rates of the Acute Coronary Syndrome (ACS) among Patients Presented with Chest Pain in the Cardiac Center

Anwar¹,

Nazim²,

Memon³

et al. 2022

PJMHS

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Background: Chest pain has been observed in the number of peoples. This is the major cause of hospital visit. Objective: The purpose of the study was to observe the acute coronary syndrome prevalence. The association of the chest pain with the cardiovascular risk factors was also studied. Study design: It is an observational study with statistical approach, conducted at Wazirabad Institute of Cardiology, Wazirabad and Khyber Teaching Hospital, Peshawar. Material and Methods: The study was conducted from Dec 2021 to May 2022. The 101 patients visited the teaching hospital of our department were included in the study. Focusing on the history of hypertension diabetes and smoking all the participants involved in the study were interviewed. The acute coronary syndrome prevalence rates were calculated. In order to find the correlation of the variables with the ACS the linear regression analysis was performed. Results: The calculated mean age was observed to be 54± 16.5 years. Out of all the patients included in the study the 75% were male participants, rest of them were female. The hypertension symptoms were observed in the 37% patients. The diabetes were observed in 26% while 23% patients were smokers. The 50% patients had non-specific chest pain while 31% patients had atypical chest pain. The 18% patients had the typical chest pain. There were total 33% patients that were suffering from acute coronary syndrome. Among these patients there were 7% patients that had unstable angina and 10% had NSTEMI, with only 17% patients suffering from STEMI. The positive correlation of acute coronary syndrome with smoking hypertension age, gender was observed. Conclusion: ACS is the lethal forms of pain. It causes serious health issues especially in patients above 40 years. The prevalence of ACS and its link with chest pain in patients at the tertiary health center was analyzed. The prevalence of the disease has strong connection with the risk factors. Keywords: Acute coronary syndrome (ACS), hypertension, atherosclerotic plaque, chest pain and risk factor.

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Section: Discussionmentioning

confidence: 53%

Estimation of Prevalence Rates of the Acute Coronary Syndrome (ACS) among Patients Presented with Chest Pain in the Cardiac Center

Anwar¹,

Nazim²,

Memon³

et al. 2022

PJMHS

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“…17 Many other studies have also shown that smoking is a major risk factor for AMI in young patients. 5,6,16,18 Smoking cessation should be encouraged as primary prevention to reduce the burden of CAD in the younger population as it can result in vasoconstriction, promotes atherosclerosis, and consequently creates a thrombotic milieu in the vessel. 5 Dyslipidemia was present in 36.3% of this study.…”

Section: Resultsmentioning

confidence: 99%

“…Other studies have reported a similar prevalence rate. 5,18,19 However, some studies have reported lower rates of obstructive CAD. 15,18,20 Non-obstructive CAD was seen in 18% of the patients in our study.…”

Section: Resultsmentioning

confidence: 99%

“…5,18,19 However, some studies have reported lower rates of obstructive CAD. 15,18,20 Non-obstructive CAD was seen in 18% of the patients in our study. In this study, the single-vessel disease was the most common (60%) finding and this predominance was similar to the other studies on young patients with ACS.…”

Section: Resultsmentioning

confidence: 99%

“…In this study, the single-vessel disease was the most common (60%) finding and this predominance was similar to the other studies on young patients with ACS. 5,15,16,18,19,21 Low prevalence of double-vessel disease suggests that extensive coronary involvement is not a common finding in young adults presenting with ACS. In the single-vessel disease group, LAD involvement was the most common infarct-related artery (40%), whereas RCA was involved in 14% and LCX in 4%.…”

Section: Resultsmentioning

confidence: 99%

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Clinical Presentation, Risk Factors, and Coronary Angiographic Profile of very Young Adults (≤30 Years) Presenting with First Acute Myocardial Infarction at a Tertiary Care Center Karachi

Khan¹,

Shaikh²,

Butt³

et al. 2022

PJMHS

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Objectives: To characterize the clinical demonstration, risk factors, echocardiographic, and coronary angiographic profile of very young individuals presenting with their first AMI at a tertiary care hospital at NICVD Karachi Sindh, Pakistan Background: Rare cases of acute coronary syndrome (ACS) occur in relatively young persons under the age of 30. In Pakistan, <2% of people have experienced an acute myocardial infarction (AMI). When it happens at this young age, ACS has a substantial impact on the patient's psyche, morbidity, and increased financial burden. Single-vessel disease and non-obstructive stenosis are considerably more common in young individuals with ACS on coronary angiography (CAG). Materials and Methods: At the Department of Cardiology NICVD Karachi, this retrospective observational research was carried out. Very young individuals (≤30 years of age) who had their first AMI from 1st January to 30th June 2019 had their medical records gathered and examined. Results: 50 young patients aged ≤30 years old were hospitalized with their first AMI. The majority of the patients were between the ages of 25–30 years. Patients had a mean age of 28.62 ± 2.04 years, and 48 of them (96%) were men. Smoking was the most frequent risk factor for CAD, accounting for 54% of cases in individuals under the age of 30. One patient presented with a complete heart block and a temporary pacemaker was inserted as a lifesaving measure. STEMI (78%) was more common as compared to NSTEMI (22%). The mean left ventricular ejection fraction was 41.4±7.6%. The single-vessel disease was the most prevalent (60%) finding. The most common culprit vessel was the LAD artery (40%) followed by the RCA (14%). The double-vessel disease was seen in 22% of individuals and the most common combination of vessels was LAD and RCA (14%). Conclusion: When compared to older patients, very young individuals showed less severe CAD, which is probably because their coronary arteries had less atherosclerosis. Smoking and dyslipidemia are the most avoidable risk factors in Pakistan's youthful population. Primary prevention, such as public awareness campaigns about the dangers of smoking, poor eating habits, and sedentary lifestyles, may assist to avert the emergence of cardiac issues in later life. Keywords: Acute coronary syndrome, coronary artery disease, smoking, young adults

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Cardiovascular Profiles of Younger and Older Coronary Artery Disease Patients in Asian and Western Regions

et al. 2023

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Epidemiological and clinical profile, management and outcomes of young patients (≤40 years) with acute coronary syndrome: A single tertiary care center study

Cited by 21 publications

References 30 publications

Estimation of Prevalence Rates of the Acute Coronary Syndrome (ACS) among Patients Presented with Chest Pain in the Cardiac Center

Estimation of Prevalence Rates of the Acute Coronary Syndrome (ACS) among Patients Presented with Chest Pain in the Cardiac Center

Clinical Presentation, Risk Factors, and Coronary Angiographic Profile of very Young Adults (≤30 Years) Presenting with First Acute Myocardial Infarction at a Tertiary Care Center Karachi

Cardiovascular Profiles of Younger and Older Coronary Artery Disease Patients in Asian and Western Regions

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