Epidemiological Studies on Proteeae Isolates from Clinical Specimens in the Laquintinie Hospital in Douala, Cameroon

Kamga, Hlf; Nsagha, DS; Assob, Jcn; Njunda, AL; Tchape, Gne

doi:10.4314/ajcem.v13i2.10

Cited by 7 publications

(7 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 12 ] However, some studies have reported a lower prevalence of 1.1%[ 13 ] and 3%[ 14 ] while other studies have shown a higher prevalence ranging from 14.4% to 28.7%. [ 15 16 17 ] In our study, the highest percentage of Proteus species was isolated from pus specimens (80.2%) followed by urine (8.9%). Similar observation has been reported by other studies whereas some studies have reported isolates more commonly from urine than other clinical specimens.…”

Section: Discussionmentioning

confidence: 63%

“…P. mirabilis was the most common (62.4%) among all the isolates which is similar to the findings of other studies. [ 11 13 15 19 ] P. mirabilis was isolated in highest number from urine as it has a higher propensity for colonizing the urinary tract due to difference in its pathogenicity. [ 11 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] We found majority of Proteus infections among the inpatients (81.18%) as compared to outpatients (18.82%) similar to other studies. [ 11 14 15 19 ] All strains of P. penneri were isolated from inpatients.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, India

Hooja

Sharma

et al. 2016

Ann Med Health Sci Res

View full text Add to dashboard Cite

Background:Proteus species cause a variety of community- and hospital-acquired illnesses. Synthesis of β-lactamases is the predominant mechanism for resistance to β-lactam antibiotics. Among the β-lactamases, extended spectrum β-lactamases (ESBLs) and AmpC β-lactamases are the most common.Aim:The objective of this study was to determine the occurrence of ESBL and AmpC β-lactamases in Proteus species among various clinical isolates at a tertiary care hospital, India.Materials and Methods:This study was done to identify various species of Proteus from clinical samples (n = 3922). Antimicrobial susceptibility was performed by Kirby–Bauer disc diffusion method. ESBL production was detected by modified double-disc synergy test and indirect modified three-dimensional tests and AmpC β-lactamase production by AmpC disc test and modified Hodge test.Results:Proteus species were isolated in 5.4% (101/1876) specimens. Three Proteus species isolated were Proteus mirabilis 62.4% (63/101), Proteus vulgaris 29.7% (30/101), and Proteus penneri 7.9% (8/101). ESBL producers confirmed by both tests were of 88.1% (89/101). Only AmpC β-lactamase was produced by four isolates. Coproduction of ESBL and AmpC β-lactamase was observed in 58.4% (52/89) of isolates. Twelve isolates were non-β-lactamase producers. Multidrug resistance (MDR) was found in 95.1% (96/101) of isolates, 50.5% (51/101) were possibly extensively drug resistant and none were pan drug resistant. None of the isolates were resistant to piperacillin-tazobactam. P. penneri isolates exhibited high resistance to most of the antibiotics.Conclusions:A high prevalence of ESBL and AmpC β-lactamases was found that concurrently showed MDR. Phenotypic methods for the detection of β-lactamases are easy and simple and can be implemented in routine diagnostic laboratories along with susceptibility testing. These data will assist the clinicians in the management and control of infections.

show abstract

Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, India

Hooja

Sharma

et al. 2016

Ann Med Health Sci Res

View full text Add to dashboard Cite

show abstract

“…They were motile, methyl red, and gelatin liquefication positive for urease, catalase, citrate, urease, and gelatin. The isolates could sour glucose on Kliger iron agar, resulting in (Alkaline) red color on the slant and lower (acidic) yellow color with gas and H2S production 16 ; oxidase, indole, and vogues-Proskauer were all negative 17,18 .…”

Section: Resultsmentioning

confidence: 99%

Molecular Exploring of Plasmid-mediated Ampc beta Lactamase Gene in Clinical Isolates of Proteus mirabilis

Al-Kraety

Al-Muhanna

Banoon

2021

View full text Add to dashboard Cite

Between September to December 2020, thirteen isolates of Proteus mirabilis were recovered among one hundred fifty; MacConkey agar was utilized to purify Gram-negative bacteria isolated from infections of the urinary tract. The primary identification of Proteus mirabilis isolates was relied on “colonial morphology, microscopic examination, and biochemical “tests; however, the confirmation of identification of antimicrobial susceptibility of isolates was conducted utilizing an automated VITEK-2 compact system. The result showed that Proteus mirabilis isolates were highly resistant to most antibiotics, making them multi-drug resistant (MDR). Phenotype methods were used to detect AmpC beta-lactamase. Initial and confirmatory methods showed that eight isolates were AmpC producers. Polymerase Chain Reaction (PCR) was employed to detect the blaampC gene.

show abstract

“…Providencia species occur in normal feces and have been isolated from epidemic and sporadic causes of diarrhea, though their importance in the causation of diarrheal disease is not easy to assess. 53 Pseudomonas aeruginosa can colonize (0%-10%) the intestine of the newborn during the first days of life. 54 Clinically, the infection may be asymptomatic at first, later developing into grayish-blue stool color or watery diarrhea, profuse vomiting, and systemic symptoms.…”

Section: Introduction and Epidemiologymentioning

confidence: 99%

Management strategies in the treatment of neonatal and pediatric gastroenteritis

Ciccarelli¹,

Stolfi²,

Caramia³

2013

IDR

View full text Add to dashboard Cite

Acute gastroenteritis, characterized by the onset of diarrhea with or without vomiting, continues to be a major cause of morbidity and mortality in children in mostly resource-constrained nations. Although generally a mild and self-limiting disease, gastroenteritis is one of the most common causes of hospitalization and is associated with a substantial disease burden. Worldwide, up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections. Prevention remains essential, and the rotavirus vaccines have demonstrated good safety and efficacy profiles in large clinical trials. Because dehydration is the major complication associated with gastroenteritis, appropriate fluid management (oral or intravenous) is an effective and safe strategy for rehydration. Continuation of breastfeeding is strongly recommended. New treatments such as antiemetics (ondansetron), some antidiarrheal agents (racecadotril), and chemotherapeutic agents are often proposed, but not yet universally recommended. Probiotics, also known as “food supplement,” seem to improve intestinal microbial balance, reducing the duration and the severity of acute infectious diarrhea. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the European Society of Paediatric Infectious Diseases guidelines make a stronger recommendation for the use of probiotics for the management of acute gastroenteritis, particularly those with documented efficacy such as Lactobacillus rhamnosus GG, Lactobacillus reuteri, and Saccharomyces boulardii. To date, the management of acute gastroenteritis has been based on the option of “doing the least”: oral rehydration-solution administration, early refeeding, no testing, no unnecessary drugs.

show abstract

Epidemiological Studies on Proteeae Isolates from Clinical Specimens in the Laquintinie Hospital in Douala, Cameroon

Cited by 7 publications

References 13 publications

Phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, India

Phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, India

Molecular Exploring of Plasmid-mediated Ampc beta Lactamase Gene in Clinical Isolates of Proteus mirabilis

Management strategies in the treatment of neonatal and pediatric gastroenteritis

Contact Info

Product

Resources

About