Epididymal Abnormalities Associated with Maldescent of the Testis

Man, de; Eckstein, H.B.

doi:10.1016/s0022-5347(17)49676-5

Cited by 16 publications

(29 citation statements)

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“…The epididymal anomalies occur in association with undescended testes in 32 to 79% of cases (1)(2)(3)(4)(5)(6)(7). In the majority of boys with a cryptorchidism, there is a patent processus vaginalis (2).…”

Section: Introductionmentioning

confidence: 99%

“…In the majority of boys with a cryptorchidism, there is a patent processus vaginalis (2). The incidence of the epididymal anomalies is higher in association with ipsilateral patency of the processus vaginalis (71 to 78%) than with ipsilateral closure (16 to 38%) (2,3,6). Mininberg and Schlossberg found that if there was a patent processus Vaginalis, 78% of boys with undescended testis had epididymal anomalies, whereas only 38% had an abnormal epididymis if there was no associated hernia (2).…”

Section: Introductionmentioning

confidence: 99%

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Epididymal Anomalies Associated with Patent Processus Vaginalis in Hydrocele and Cryptorchidism

Han

Kang

2002

J Korean Med Sci

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The epididymal anomalies and patent processus vaginalis are frequently seen in patients with cryptorchidism or hydrocele. We performed a prospective study on the relationship between the epididymal anomalies and the patency of the processus vaginalis in boys with hydrocele (190 cases) or cryptorchidism (89 cases) who were treated from August 1997 to February 2000 (mean age, 51 months; range, 12 to 152 months). The epididymal anomalies were observed with an overall frequency of 48%. Closed, partially closed, and open processus vaginalis were associated with an epididymal anomaly in 14, 38, and 65% of cases, respectively. The epididymal anomalies were more common in association with undescended (61%) than with descended (43%) testes without statistical significance (p=0.415). Incomplete attachment of the caput epididymis was the most common anomaly (35%), followed by detachment of caput and cauda epididymis (31%), cauda epididymis (24%), and long looping epididymis (10%). These data showed that the epididymal anomalies were strongly associated with the patency of the processus vaginalis irrespective of testicular descent (p<0.001), and they provide further evidence for the hypothesis that a common stimulus, possibly androgens, may be required for the epididymal development and obliteration of the processus vaginalis.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Epididymal Anomalies Associated with Patent Processus Vaginalis in Hydrocele and Cryptorchidism

Han

Kang

2002

J Korean Med Sci

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“…Çoğu yazar, epididim anomalilerinin inmemiş testisli hastalarda daha sık görüldüğünü (% 32-43) rapor etmişlerdir (9,10) . Favorito ve ark.…”

Section: Discussionunclassified

“…(7) epididim anomalisi oranının normal fetuslerde % 4 iken inmemiş testis olan fetuslerde % 35 olduğunu göstermişlerdir. İnme-miş testis hastalarında tespit edilen epididim anomalileri çoğunlukla, epididm yapılarının uzaması veya epididimin açılaşması olarak tariflenen, duktal süs-pansiyon anomalileridir (9,10,12,16,18) . DePalma ve ark.…”

Section: Discussionunclassified

What is the relationship between epididymal anomalies and cryptorchidism? A rare case, new treatment proposal and review of the literature

Acer¹

2012

TCCD

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“…With the retention of the testicles in the abdominal cavity, the seminiferous tubules become atrophic as a result of the increase in temperature, which is unfavorable for spermatogenesis [10,11]. Although the testis are severely damaged, cryptorchidism may be considered a primary congenital illness of both testis and spermatic ducts, since that gross structural abnormalities have been often described in the human epididymis and vas deferens with cryptorchidic testes [7,8,12,17,18]. Furthermore, some histological alterations have been also described to epididymis and vas deferens from cryptorchidic testis [8,18].…”

Section: Introductionmentioning

confidence: 99%

Does Orchidopexy Revert the Histological Alterations in Epididymal and Vas Deferens Caused by Cryptorchidism?

Arroteia¹,

Joazeiro²

2005

Archives of Andrology

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&Cryptorchidism is a pathological condition in which the testicles are retained in the abdominal cavity, resulting in atrophic seminiferous tubules. Some gross structural abnormalities and histological alterations have been described in the epididymis and vas deferens in humans with cryptorchidic testes. Orchidopexy surgery restores testicular spermatogenesis in experimental and clinical procedures, but it is still unclear whether histological changes in the epididymis and vas deferens caused by cryptorchidism may be reverted by orchidopexy. The aim of this study was to evaluate the histological changes in the epididymis and vas deferens following experimental uniand bilateral cryptorchidism in mature and immature mice, and to determine whether alterations could be reversed by orchidopexy. Young and adult C57 BL6 mice were randomized into three groups: control mice, bi=unilaterally cryptorchidic mice and bilaterally cryptorchidic mice with orchidopexy. After evaluation of testis, epididymis and vas deferens, there were no histological alterations in contralateral epididymis of mice unilaterally cryptorchidic. Ipsilateral epididymis of unilaterally cryptorchidic mice and epididymis from bilaterally cryptorchidic mice showed significant histological alterations. Orchuidopexy restored normal spermatogenesis and the histological features of epididymis. It would appear that persistent male infertility clinically observed after orchidopexy could not be related to histological alteration in the testis and epididymis. Development and maintenance of the vas deferens seems to be controlled independently of the epididymis since it was not altered by cryptorchidism condition.

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Epididymal Abnormalities Associated with Maldescent of the Testis

Cited by 16 publications

References 0 publications

Epididymal Anomalies Associated with Patent Processus Vaginalis in Hydrocele and Cryptorchidism

Epididymal Anomalies Associated with Patent Processus Vaginalis in Hydrocele and Cryptorchidism

What is the relationship between epididymal anomalies and cryptorchidism? A rare case, new treatment proposal and review of the literature

Does Orchidopexy Revert the Histological Alterations in Epididymal and Vas Deferens Caused by Cryptorchidism?

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