Epidural anaesthesia for Caesarean section in a patient with von Hippel-Lindau disease

Demiraran, Yavuz; Özgön, M.; Utku, Tuğhan; Bozkurt, Pervin

doi:10.1046/j.0265-0215.2000.00824.x

Cited by 10 publications

(9 citation statements)

References 17 publications

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“…Of the 22 cases involving VHLD patients, 3 were pediatric patients 8 , 9 , 10 and 19 were adults. 1 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 There were a total of 32 surgical procedures performed among the 22 patients, including 2 cases of spontaneous labor. 13 were obstetrical cases, 1 , 11 , 12 , 13 , 14 , 16 , 17 , 18 , 20 , 22 , 23 , 25 , 27 10 were neurosurgical procedures, 9 , 13 , 14 , 15 , 17 , 19 , 21 , 24 , 25 , 28 and 9 were pheochromocytoma resections.…”

Section: Discussionmentioning

confidence: 99%

“…1 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 There were a total of 32 surgical procedures performed among the 22 patients, including 2 cases of spontaneous labor. 13 were obstetrical cases, 1 , 11 , 12 , 13 , 14 , 16 , 17 , 18 , 20 , 22 , 23 , 25 , 27 10 were neurosurgical procedures, 9 , 13 , 14 , 15 , 17 , 19 , 21 , 24 , 25 , 28 and 9 were pheochromocytoma resections. 8 , 9 , 10 , 11 , 15 , 19 , 24 , 26 13 of the 22 cases reported single surgical procedures performed 1 , 8 , 10 , 12…”

Section: Discussionmentioning

confidence: 99%

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Thoracic epidural analgesia in a patient with von Hippel‐Lindau disease

Yap

Hanada

Ravindranath

et al. 2022

Clinical Case Reports

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Thoracic epidural analgesia in a patient with von Hippel‐Lindau disease

Yap

Hanada

Ravindranath

et al. 2022

Clinical Case Reports

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“…Although regional anesthesia is usually employed for cesarean sections, a standard anesthetic method for systemic VMs, such as BRBNS and Von Hippel-Lindau disease, remains controversial, particularly in cases of nervous system involvement [13–15]. General anesthesia was selected because of the following reasons: MRI revealed no VMs in the patient's air way, direct visual guidance during the procedure is preferred, and spinal or epidural anesthesia may lead to secondary spinal epidural hematoma induced by direct or indirect injury to the vasculature [16].…”

Section: Discussionmentioning

confidence: 99%

Familial Blue Rubber Bleb Nevus Syndrome in Pregnancy with Spinal Epidural Involvement

Ochiai

Miyakoshi

Yakubo

et al. 2013

Case Reports in Obstetrics and Gynecology

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Blue rubber bleb nevus syndrome (BRBNS) is a rare vascular disorder characterized by multiple venous malformations (VMs) of the skin, gastrointestinal tract, and other organs. To date, several cases of sporadic BRBNS involving various parts of the pregnant woman's body have been reported; however, BRBNS in pregnancy with spinal epidural involvement has not been reported. Here, we describe the clinical features and management of familial BRBNS in pregnancy. The patient presented with multiple VMs on her head, neck, floor of the mouth, trunk, leg, foot, and vulva and spinal epidural lesions. The patient's mother and sister also exhibited multiple VMs similar lesions, indicating a familial form of BRBNS. Cesarean section under general anesthesia was performed, and a healthy male neonate was delivered. The mother's postoperative course was uneventful and her VMs decreased in size after delivery. Physicians should consider the possibility of systemic diseases and familial inheritance in cases of VMs.

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“…3,4 VHL is inherited in an autosomal dominant fashion and arises secondary to a mutation in the VHL tumour suppressor gene involved in cell cycle regulation and angiogenesis. 5 The incidence is one in 35,000-65,000. 6 Haemangioblastomas may occur at various sites within the central nervous system although the cerebellum is the commonest location.…”

Section: Discussionmentioning

confidence: 99%

“…9 There is a reported 3-10% recurrence rate after resection and long-term follow-up for these patients is therefore advised. 5 The progress of asymptomatic haemangioblastomas in pregnancy is more difficult to determine from the literature. Grimbert et al looked retrospectively at 56 pregnancies in 30 women with VHL of whom four had central nervous system haemangioblastomas.…”

Section: Discussionmentioning

confidence: 99%

Cerebellar haemangioblastoma presenting with dizziness in pregnancy: case report and review of the literature

et al. 2009

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Summary: Cerebral neoplasms are uncommon in pregnancy but should be considered in any pregnant woman with new onset neurological symptoms and signs. We report a case of cerebellar haemangioblastoma presenting in pregnancy and discuss the clinical presentation, diagnosis, surgical management and medical literature surrounding the condition.Keywords: pregnancy, maternal medicine, cerebellar haemangioblastoma, brain tumour, outcome CASEA 33-year-old Angolan woman presented to the antenatal day assessment unit (ADAU) at 28 weeks complaining of dizziness. She worked as a cleaner, was married, a Jehovah's Witness and a French speaker, with limited English vocabulary having arrived in the UK six years previously. Her body mass index was 26 and she had no past medical history of note. This was her fourth pregnancy having had a prior first trimester miscarriage and two uncomplicated spontaneous vaginal deliveries, the last of which was three years previously.On arrival on the ADAU she reported a 1-2-week history of right-sided headache and neck pain in association with vomiting. Temperature, pulse blood pressure and physical examination were all unremarkable and thyroid function tests were within normal limits. The patient was discharged with a diagnosis of dehydration secondary to vomiting as a result of a presumed urinary tract infection. She re-presented to the ADAU one week later with persistent vomiting, dizziness and epigastric pain when a diagnosis of viral labyrinthitis was presumed. Again temperature, pulse blood pressure and physical examination were unremarkable. However, she was admitted for intravenous rehydration. The following day her symptoms persisted. Closer questioning revealed the dizziness had been present for four weeks with vomiting for two weeks and the headache of gradual onset over the preceding three weeks. There was no history to suggest middle ear disease and she was not on ototoxic medications.On examination of the central nervous system the visual acuity was noted to be grossly intact, and fundoscopy normal. Pupils were symmetrical, reactive and accommodating. She had impairment of lateral gaze on both sides consistent with bilateral lateral rectus (or VI) palsies. There was no facial weakness or sensory loss and no bulbar signs. Peripheral nervous system examination of the upper and lower limbs was normal and she had down-going plantars. Sensation was normal. Cerebellar examination revealed moderate dysdiadochokinesis of the left hand with mild past pointing. There was marked truncal ataxia, with an unsteady broad based gait. In view of the neurological signs a magnetic resonance imaging (MRI) scan was arranged.The MRI scan showed a cystic lesion with a peripheral nodule within the cerebellum with no evidence of bleeding, the features being consistent with a haemangioblastoma (Figure 1). Gadolinium was not administered because of the pregnancy. Transfer to an obstetric unit with neurosurgical services on site was arranged. Steroids were given to promote fetal lung maturity in the event of ...

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Epidural anaesthesia for Caesarean section in a patient with von Hippel-Lindau disease

Cited by 10 publications

References 17 publications

Thoracic epidural analgesia in a patient with von Hippel‐Lindau disease

Thoracic epidural analgesia in a patient with von Hippel‐Lindau disease

Familial Blue Rubber Bleb Nevus Syndrome in Pregnancy with Spinal Epidural Involvement

Cerebellar haemangioblastoma presenting with dizziness in pregnancy: case report and review of the literature

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