Epidural Lipomatosis

Abstract

<jats:sec> <jats:title>Object</jats:title> <jats:p>Idiopathic symptomatic spinal epidural lipomatosis (SEL) is a rare condition, and few reports have discussed diagnostic imaging criteria. To evaluate factors relating to its clinical symptoms, correlations between clinical features and the presence of spinal epidural fat were investigated, and the literature concerning idiopathic SEL was reviewed.</jats:p></jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>Morphological gradings of epidural fat were evaluated in seven patients with idiopathic SEL by using magnetic resonance (MR) imaging. In addition, body mass index (BMI), the number of involved vertebral levels, grade, and preoperative Japanese Orthopaedic Association (JOA) score were analyzed. Surgery resulted in symptomatic relief, with a mean JOA score recovery rate of 67.4%. Grading of epidural fat tended to display a slight negative correlation with preoperative JOA score, whereas a strong significant positive correlation was found between the number of involved vertebral levels and BMI.</jats:p></jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>The number of involved vertebral levels and obesity are strongly correlated, whereas severity of dural compression is not always significantly associated with neurological complications. These results indicate that epidural fat of the lumbar spine contributes to neurological deficits. In addition, weight-reduction therapy appears to decrease the number of vertebral levels involved. Magnetic resonance imaging–based grading is helpful for the diagnosis and evaluation of idiopathic lumbar SEL. Moreover, symptoms and neurological findings are important for determining the surgical approach.</jats:p></jats:sec>

Lipomatose epidural idiopática familiar: relato de três casos e revisão da literatura

“…A ressonância é o exame de escolha, sugerindo o diagnóstico quando a espessura da camada de gordura epidural ultrapassa 6 mm. [10][11][12] Tomografia e mielografia podem ser utilizadas para o diagnóstico, mas são menos eficazes. 3 O estudo do líquor pode evidenciar um aumento no número de proteínas, que significa apenas bloqueio de circulação liquórica.…”