2024
DOI: 10.1002/dvg.23593
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Epigenetic programming of stochastic olfactory receptor choice

Nusrath Yusuf,
Kevin Monahan

Abstract: SummaryThe mammalian sense of smell relies upon a vast array of receptor proteins to detect odorant compounds present in the environment. The proper deployment of these receptor proteins in olfactory sensory neurons is orchestrated by a suite of epigenetic processes that remodel the olfactory genes in differentiating neuronal progenitors. The goal of this review is to elucidate the central role of gene regulatory processes acting in neuronal progenitors of olfactory sensory neurons that lead to a singular expr… Show more

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References 117 publications
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