Hepatitis B Virus - Pathogenesis and Therapeutic Approaches [Working Title] 2024
DOI: 10.5772/intechopen.1005972
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Epigenetic Regulation in the Development of Hepatitis B Virus-related Hepatocellular Carcinoma

Shahab Mahmoudvand,
Zahra Ramezannia,
Arastoo Kaki and Somayeh Shokri

Abstract: Viruses are always dependent on their host in many ways. They especially rely on the cellular machinery of the host cell for their replication. In this regard, epigenetic regulation is one of the influential factors during viral infections. Hepatitis B virus (HBV) is involved in developing hepatocellular carcinoma (HCC) by different mechanisms. Both the HBc and HBx viral proteins are able to interfere with the host cell epigenetic machinery in different ways. While the role of HBc has not yet been defined in d… Show more

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