2008
DOI: 10.1016/j.biopsych.2008.04.030
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Epilepsy in Autism is Associated with Intellectual Disability and Gender: Evidence from a Meta-Analysis

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Cited by 436 publications
(371 citation statements)
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“…This is supported by Pavone, Incorpora, Fiumara, Parano, Trifiletti, & Ruggieri (2004) who found the prevalence to be 6% in children with ASD without additional neurological disorders. More males than females had epilepsy in the current study, which is in contrast to the Amiet et al's (2008) study.…”
Section: Discussioncontrasting
confidence: 93%
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“…This is supported by Pavone, Incorpora, Fiumara, Parano, Trifiletti, & Ruggieri (2004) who found the prevalence to be 6% in children with ASD without additional neurological disorders. More males than females had epilepsy in the current study, which is in contrast to the Amiet et al's (2008) study.…”
Section: Discussioncontrasting
confidence: 93%
“…The more severe the ID, the more prevalent epilepsy is and the greater part of statistical association between epilepsy and ID in autism relates to moderate and severe ID (Amiet et al, 2008). Amiet et al (2008) also found that more females than males with autism had a diagnosis of epilepsy, where the prevalence of epilepsy was 34.5% in females versus 18.5% in males. Furthermore, Tuchman et al (1991) found that girls with autism had lower cognitive ability than boys.…”
mentioning
confidence: 95%
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“…The rate reported here of 2 out of 100 (2%) is more in keeping with rates in the general population (2.9%; U.S. Department of Health and Human Services, 2007) and very low for typical ASD samples. However, the current sample does not include individuals with learning disabilities, and previous studies have suggested that intellectual impairment mediates the association between ASD and epilepsy (Amiet et al 2008). It is worth noting, that of the two individuals with ASD who had epilepsy, one was found to have a learning disability (and was not included in the analysis) and the other had epilepsy possibly associated with alcohol misuse.…”
Section: Discussionmentioning
confidence: 99%
“…A prominent comorbidity is that of children diagnosed with both autism and epilepsy (Berg et ............................................................................................................................................................ et al, 2011). Approximately 20-30% of children with autism have seizures, with the highest rate in autistic children with severe intellectual disabilities (Amiet et al, 2008;Berg et al, 2010;Tuchman et al, 2010). Moreover, six percent of children who suffer a seizure very early in life (aged 1-2 years) develop ASDs with intellectual disabilities (Clarke et al, 2005).…”
Section: Comorbidity With Autismmentioning
confidence: 99%