2015
DOI: 10.1016/j.ajem.2015.02.049
|View full text |Cite
|
Sign up to set email alerts
|

Epistaxis complicated by rivaroxaban managed with topical tranexamic acid

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
5
0

Year Published

2015
2015
2023
2023

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(5 citation statements)
references
References 18 publications
0
5
0
Order By: Relevance
“…However, a recent review of epistaxis patients found a lack of studies including patients treated with DOAC and could not identify a direct comparison of patients under DOAC or VKAs . Only a few case reports about the management of patients with epistaxis on DOAC therapy exist . Although severe bleeding complications in DOAC patients are rare, epistaxis was found to be one of the most frequent minor bleeding complication in patients on DOAC therapy …”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, a recent review of epistaxis patients found a lack of studies including patients treated with DOAC and could not identify a direct comparison of patients under DOAC or VKAs . Only a few case reports about the management of patients with epistaxis on DOAC therapy exist . Although severe bleeding complications in DOAC patients are rare, epistaxis was found to be one of the most frequent minor bleeding complication in patients on DOAC therapy …”
Section: Introductionmentioning
confidence: 99%
“…2 Only a few case reports about the management of patients with epistaxis on DOAC therapy exist. 6,7 Although severe bleeding complications in DOAC patients are rare, epistaxis was found to be one of the most frequent minor bleeding complication in patients on DOAC therapy. 8 To our knowledge, no study has yet described the characteristics of ED patients with epistaxis during DOAC therapy, nor did we find a direct comparison of DOACs and VKAs in patients presenting with epistaxis.…”
mentioning
confidence: 99%
“…Tranexamic acid inhibits the binding of plasminogen to fibrin, thereby preventing clot breakdown. 12,13,28 There is no standard classification for the severity of bleeding, and it may vary from patient to patient. Specific treatment depends on the involved artery, and the correct identification of the bleeding artery is the most basic measure for an effective treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Patients should also be assessed for any new interacting medications that may increase DOAC levels. Several case reports of epistaxis in patients taking dabigatran or rivaroxaban have been published, 61-66 but the management strategies employed were variable (including temporarily or permanently stopping the DOAC, changing the DOAC to a vitamin K antagonist or using topical tranexamic acid), offering little insight into general recommendations.…”
Section: Managementmentioning
confidence: 99%