Epithelial-neuronal-immune cell interactions: Implications for immunity, inflammation, and tissue homeostasis at mucosal sites

Emanuel, Elizabeth; Arifuzzaman, Mohammad; Artis, David

doi:10.1016/j.jaci.2024.02.004

Journal of Allergy and Clinical Immunology

2024

DOI: 10.1016/j.jaci.2024.02.004

|View full text |Cite

Epithelial-neuronal-immune cell interactions: Implications for immunity, inflammation, and tissue homeostasis at mucosal sites

Elizabeth Emanuel,

Mohammad Arifuzzaman,

David Artis

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 174 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Epithelial-immune interactions govern type 2 immunity at barrier surfaces

Lopez Espinoza,

Christopher,

Tait Wojno

2024

Current Opinion in Immunology

View full text Add to dashboard Cite

Epithelial-immune interactions govern type 2 immunity at barrier surfaces

Lopez Espinoza,

Christopher,

Tait Wojno

2024

Current Opinion in Immunology

View full text Add to dashboard Cite

Stressing out the intestinal microbiota via a brain-neuroglandular circuit

Zhang,

Artis

2024

Cell Res

View full text Add to dashboard Cite

Current applications of intestinal organoids: a review

Xiang,

Wang,

2024

Stem Cell Res Ther

View full text Add to dashboard Cite

In the past decade, intestinal organoid technology has paved the way for reproducing tissue or organ morphogenesis during intestinal physiological processes in vitro and studying the pathogenesis of various intestinal diseases. Intestinal organoids are favored in drug screening due to their ability for high-throughput in vitro cultivation and their closer resemblance to patient genetic characteristics. Furthermore, as disease models, intestinal organoids find wide applications in screening diagnostic markers, identifying therapeutic targets, and exploring epigenetic mechanisms of diseases. Additionally, as a transplantable cellular system, organoids have played a significant role in the reconstruction of damaged epithelium in conditions such as ulcerative colitis and short bowel syndrome, as well as in intestinal material exchange and metabolic function restoration. The rise of interdisciplinary approaches, including organoid-on-chip technology, genome editing techniques, and microfluidics, has greatly accelerated the development of organoids. In this review, VOSviewer software is used to visualize hot co-cited journal and keywords trends of intestinal organoid firstly. Subsequently, we have summarized the current applications of intestinal organoid technology in disease modeling, drug screening, and regenerative medicine. This will deepen our understanding of intestinal organoids and further explore the physiological mechanisms of the intestine and drug development for intestinal diseases.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Epithelial-neuronal-immune cell interactions: Implications for immunity, inflammation, and tissue homeostasis at mucosal sites

Cited by 3 publications

References 174 publications

Epithelial-immune interactions govern type 2 immunity at barrier surfaces

Epithelial-immune interactions govern type 2 immunity at barrier surfaces

Stressing out the intestinal microbiota via a brain-neuroglandular circuit

Current applications of intestinal organoids: a review

Contact Info

Product

Resources

About