Epstein-Barr virus-associated gastric ulcer mimicking gastric neoplasia: a case report

Cătinean, Adrian; Motocu, R; Fetică, Bogdan; Mezei, Anita

doi:10.11152/mu-1560

Cited by 6 publications

(3 citation statements)

References 8 publications

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“…Waage et al reported that strain ratio measurements in strain elastography were significantly different between adenomas and adenocarcinomas. Moreover, the use of strain ratio measurements to discriminate benign lesions from malignant ones offers high sensitivity (82.0%), specificity (86.0%), and accuracy (84.0%), meaning that strain elastography can provide added value when used in conjunction with endorectal US [ 8 , 9 ]. These images, however, do not directly quantify the elasticity of the tumor.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Ultrasound Elastography in the Assessment of Rectal Tumors: How Well Does It Work in Clinical Practice?

et al. 2021

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Endorectal ultrasound applications in the evaluation of rectal tumors could be a useful tool in achieving proper staging of rectal cancer. The purpose of this study was to compare the efficacy of rectal tumor staging by flexible endoscopic ultrasound (EUS) with real-time elastography (RTE) using the gold standard post-surgery histological analysis of the resected tissue as the control. The second aim of our research was to establish cutoff values for the EUS-RTE strain ratio corresponding to stages by independently comparing the stiffness values obtained with histology and EUS-RTE staging in order to minimize observation bias. We evaluated the records of 130 patients with a rectal tumor confirmed by biopsy. EUS was used in 70 patients, EUS-RTE—in the other 60. We found no statistically significant differences in staging accuracy when comparing EUS to EUS-RTE. Through a correspondence method between staging assessment and the EUS-RTE stain ratio, we identified cutoff intervals for T2, T3, and T4 staging that were nonoverlapping and proved to be statistically significant in terms of EUS-RTE values (significantly different ascending values from one interval to the other). We found that EUS-RTE offers slightly better, although not statistically significant sensitivity and specificity for T and N stage predictions compared to 2D EUS. Our results showed that EUS-RTE offers slightly higher sensitivity and specificity compared to EUS. Reliable cutoff intervals were found for strain rate elastography, previously available only for shear wave elastography (SWE) which is currently unavailable on any EUS system. Thus, these commonly available EUS-RTE systems can serve as a complementary tool in the staging of rectal tumors.

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Section: Discussionmentioning

confidence: 99%

Endoscopic Ultrasound Elastography in the Assessment of Rectal Tumors: How Well Does It Work in Clinical Practice?

et al. 2021

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“…Analyzing the possible prognostic value of Hep Par-1 in patients with surgically resected HCC, Mondada et al [21] finds Hep Par-1 expression, considering it a favorable prognostic factor in small size tumors. Otherwise, tumor size and growth has been already linked to multiple cellular and plasmatic markers hyper expression [22][23][24][25].…”

Section: Fig 1 Staging Of the Studied Hepatic Carcinomasmentioning

confidence: 99%

The Diagnostic Value of Hepatocyte Paraffin Antibody 1 in Differentiating Hepatocellular Carcinoma from non-hepatic Tumors

2020

Rev.Chim.

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The paper presents approaches the topic of hepatocellular carcinoma (HCC) differential diagnosis with various other malignant tumors, as such differentiation can be in many cases performed only based on a thorough immunohistochemical marker designed for hepatocellular differentiation. Hepatocyte paraffin-1(Hep Par-1), is a specific antibody for hepatocellular tissue that is represented within both healthy and malignant hepatic cells. The paper evaluated the expression of Hep Par-1 on paraffin tissue acquisitions of selected cases of resecable hepatocellular carcinoma referred for curative surgery (20 cases). For the experimental part, mouse anti-human hepatocyte monoclonal antibodies, Hepatocyte Ab1,and diluted clones of OCH1E5 with the EnVision technique have been used. The results were suggestive for positive expression of Hep Par-1 in 15 of the 20 cases of HCC (75%), with various degrees secondary to the differentiation degree (which was positive in all 15 G1-G2 HCCs and negative in 5 G3-G4 HCCs); on the other hand, the study showed a non-homogenous and focal Hep Par-1 distribution malignant tissue engaging a uniform staining of the non-tumorous liver tissue surrounding the lesion. The study did not show Hep Par-1 immunostaining in non-hepatocytic tumors, excepting some focal expression on a gastric adenocarcinoma with clear patchy expression. Our research confirms that Hep Par-1 can be considered a valuable marker in the diagnosis of HCC, although not totally specific; thus, it should be used in a conjugated manner with various other markers useful in hepatocellular differentiation. Keywords: hepatocellular carcinoma, metastatic carcinoma, Hep Par-1, differential diagnosis of HCC

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“…Perforations represent a significant part of the possible complications related to upper gastrointestinal procedures, with an increased incidence among interventional endoscopic techniques (1). Both endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy have an overall complications-associated rate between 0.09% and 1.67% (2, 3) with duodenal perforations representing 0.08 % to 0.6% (4,5,6) or roughly one third of the total ERCP related perforations.…”

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ERCP-related perforations: covert or overt adverse events? A prospective case series

Roxana

Bălan

Sfarti

et al. 2021

MSJ

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Epstein-Barr virus-associated gastric ulcer mimicking gastric neoplasia: a case report

Cited by 6 publications

References 8 publications

Endoscopic Ultrasound Elastography in the Assessment of Rectal Tumors: How Well Does It Work in Clinical Practice?

Endoscopic Ultrasound Elastography in the Assessment of Rectal Tumors: How Well Does It Work in Clinical Practice?

The Diagnostic Value of Hepatocyte Paraffin Antibody 1 in Differentiating Hepatocellular Carcinoma from non-hepatic Tumors

ERCP-related perforations: covert or overt adverse events? A prospective case series

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