Epstein-Barr virus hepatitis can cause transient hepatopulmonary syndrome

Abstract

IntroductionHepatopulmonary syndrome is commonly seen in the patients with chronic liver disease. Acute liver diseases are rarely associated with HPS. We have reported here a case of Transient HPS caused by Epstein-Barr virus hepatitis.Case reportThe patient was a 31 years old man that came to hospital due to RUQ pain and yellowish skin. In examination the patient was tachypnic and O2 saturation was 71% with prominent JVP. ver enzyme and bilirubin were high. All viral hepatitis was negative except anti viral capsid antigen-antibody of EBV. In Blood gas PaO2 was 54 mmHg, O2 saturation 73% and alveolar-arterial gradient was 18 mmHg. Stress Echocardiography with saline injection reported pulmonary arterial pressure 32 cmHg with delayed opacification of left atrium.Conclusiontransient HPS can be manifestation in the acute hepatitis caused by EBV infection.

Chronic Hepatitis C with Cyanosis

“…Although there are no established medical therapies for HPS, surprisingly, some publications reported spontaneous resolution of HPS [10]. Inferences of findings between the studies about effective experimental treatments are hindered by the relatively small number of participants and inconsistent results [11, 12].…”