Equilibrium and kinetic studies for removal of antiviral sofosbuvir from aqueous solution by adsorption on expanded perlite: Experimental, modelling and optimization

Babas, H.; Kaichouh, G.; Khachani, Mariam; Karbane, Miloud El; Chakir, Ahmed; Guenbour, A.; Bellaouchou, A.; Warad, Ismail; Zarrouk, A.

doi:10.1016/j.surfin.2021.100962

Cited by 20 publications

(15 citation statements)

References 42 publications

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“…These techniques are used in conjunction with thermal analysis (DTA) and thermogravimetric analysis (TGA) to follow the thermal evolution of these Xerogel phosphates, Thermogravimetric (TGA) and differential thermal analysis (DTA) (Labsys Evo1F Setaram). Morphological surface features were examined by applying Jeol JSM-IT100 InTouchScope™ Scanning Electron Microscope (SEM) connected to a microanalyzer EDS [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

Statistical optimization of amorphous iron phosphate: inorganic sol–gel synthesis-sodium potential insertion

et al. 2021

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Iron phosphate, Fe2 (HPO4)3*4H2O, is synthesized at ambient temperature, using the inorganic sol–gel method coupled to the microwave route. The experimental conditions for the gelling of Fe (III)-H3PO4 system are previously defined. Potentiometric Time Titration (PTT) and Potentiometric Mass Titration (PMT) investigate the acid–base surface chemistry of obtained phosphate. Variations of surface charge with the contact time, Q a function of T, are examined for time contact varying in the range 0–72 h. The mass suspensions used for this purpose are 0.75, 1.25 and 2.5 g L−1. The point of zero charge (PZC) and isoelectric point (IEP) are defined using the derivative method examining the variations $$\frac{{{\text{dpH}}}}{{{\text{d}}t}} = f\left( {{\text{pH}}} \right)$$ dpH d t = f pH , at lower contact time. A shift is observed for PZC and IEP towards low values that are found to be 2.2 ± 0.2 and 1.8 ± 0.1, respectively. In acidic conditions, the surface charge behavior of synthesized phosphate is dominated by $$\overline{{ > {\text{POH}}}}$$ > POH ¯ group which pKa = 2.45 ± 0.15. Q against T titration method is performed for synthesized Fe2 (HPO4)3*4H2O in NaCl electrolytes. The maximal surface charge (Q) is achieved at the low solid suspension. Hence, for m = 0.75 g L−1, Q value of 50 coulombs is carried at μ = 0.1 and pH around 12, while charge value around 22 coulombs is reached in the pH range: 3–10. The effect of activation time, Q and pH on sodium insertion in iron phosphate, were fully evaluated. To determine the optimal conditions of the studied process, mathematical models are used develop response surfaces in order to characterize the most significant sodium interactions according to the variation of the pH, Q, the contact time and the contents of the synthesized material.

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Section: Methodsmentioning

confidence: 99%

Statistical optimization of amorphous iron phosphate: inorganic sol–gel synthesis-sodium potential insertion

et al. 2021

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“…Table 3 shows the maximum and minimum values for each component. The choice of the limits of the investigated region was determined using data from the literature (Colombo et al 2016 ; Attimarad et al 2020 ; Babas et al 2021 ). A total of 15 tests were required to optimize AVS extraction efficiency.…”

Section: Methodsmentioning

confidence: 99%

Cuttlefish bone powder as an efficient solid-phase extraction sorbent of anti-SARS-CoV-2 drugs in environmental water

et al. 2022

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Many antiviral drugs were developed to counteract coronavirus disease, 2019 (COVID-19) with severe acute respiratory syndrome. Therefore, the scientific community's efforts have focused on the detection and quantification of antiviral compounds currently being tested for COVID-19 treatment. Cuttlefish bone powder (CFBP) has been used for the first time as solid-phase extraction (SPE) sorbent for the extraction of SARS CoV-2 antiviral drugs (chloroquine, ritonavir and indomethacin) from water samples. An effective and sensitive method was developed by combining SPE and liquid chromatography- UV detection (LC-UV). An experimental design was applied for the optimization of extraction process. Experimental variables were optimized using Doehlert matrix. The developed method included 50 mg of CFBP sorbent, 20 mL of water sample at pH = 9 and 5 mL of ACN/KH 2 PO 4 buffer solution (80:20, v/v) in the elution step. For validation of the method, selectivity, linearity precision, and sensitivity were evaluated. Extraction recovery percentage of all Sars cov-2 antivirals were above 98.2%. The detection and quantification limits were between 0.1 and 0.5 µg L −1 and 0.6 and 2 µg L −1 , respectively. The current study suggested that CFBP has the application potential for the enhanced SPE of SARS CoV-2 antiviral drugs from water samples.

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“…Several methods such as liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , high-performance liquid chromatography (HPLC) [59] , [60] , [61] , [62] , [63] , [64] , ultra-performance liquid chromatography with positive electrospray ionization tandem spectrometry (UPLC-MS/MS) [65] and (ultraviolet) UV–Vis spectrophotometer [66] , [67] have been used to determine antiviral drugs from aqueous samples. In most cases, liquid chromatography-tandem mass spectrometry (LC-MS/MS) is used to quantify antiviral drugs from environmental waters and wastewaters due to high selectivity, accuracy, sensitivity and flexibility [68] , [69] .…”

Section: Occurrence and Determination Methods In The Aquatic Environmentmentioning

confidence: 99%

A sustainable approach for the removal methods and analytical determination methods of antiviral drugs from water/wastewater: A review

Eryıldız

Gül

Koyuncu

2022

Journal of Water Process Engineering

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Equilibrium and kinetic studies for removal of antiviral sofosbuvir from aqueous solution by adsorption on expanded perlite: Experimental, modelling and optimization

Cited by 20 publications

References 42 publications

Statistical optimization of amorphous iron phosphate: inorganic sol–gel synthesis-sodium potential insertion

Statistical optimization of amorphous iron phosphate: inorganic sol–gel synthesis-sodium potential insertion

Cuttlefish bone powder as an efficient solid-phase extraction sorbent of anti-SARS-CoV-2 drugs in environmental water

A sustainable approach for the removal methods and analytical determination methods of antiviral drugs from water/wastewater: A review

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