Eradication of Peste des Petits Ruminants Virus and the Wildlife-Livestock Interface

Fine, Amanda E.; Pruvot, Mathieu; Benfield, Camilla T. O.; Caron, Alexandre; Cattoli, Giovanni; Chardonnet, Philippe; Dioli, Maurizio; Dulu, Thomas D.; Gilbert, Martin; Kock, Richard; Liu, Juan; Mariner, Jeffrey C.; Ostrowski, Stéphane; Parida, Satya; Fereidouni, Sasan; Shiilegdamba, Enkhtuvshin; Sleeman, Jonathan M.; Schulz, Claudia; Soula, Jean-Jacques; Stede, Yves Van der; Tekola, Berhe G.; Walzer, Chris; Zuther, Steffen; Njeumi, Félix; Participants, Meeting

doi:10.3389/fvets.2020.00050

Cited by 49 publications

(64 citation statements)

References 46 publications

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“…Peste des Petits Ruminants may also be of wildlife conservation concern (Fine et al., 2020). Different PPR outbreaks causing high mortality have been documented in captive species such as gazelles ( Gazella spp.…”

Section: Resultsmentioning

confidence: 99%

Serosurvey of Peste des Petits Ruminants in southern Spain

Cano‐Terriza

Jiménez‐Martín

Jiménez‐Ruiz

et al. 2020

Transbound. Emerg. Dis.

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Section: Resultsmentioning

confidence: 99%

Serosurvey of Peste des Petits Ruminants in southern Spain

Cano‐Terriza

Jiménez‐Martín

Jiménez‐Ruiz

et al. 2020

Transbound. Emerg. Dis.

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“…To date, there is no evidence that wildlife can maintain the disease in a way significant to the global epidemiological control of PPR. The possible areas for research at the livestock/wildlife interface have already been extensively reviewed [12]. But is missing in this review, the research on wildlife and non-conventional species as well as the role of wildlife and wildlife/livestock interface in the epidemiology of PPR in different regions in order to address knowledge gaps.…”

Section: Infection Of Wildlife and Other Speciesmentioning

confidence: 99%

“…Epidemiology of the disease could focus on the potential role of wildlife and other animal species (including non-typical species in surveillance) to inform sheep and goat vaccination plans (PPRV transmission studies using virulent PPRV strains in sheep and goats and also non-typical species), There are now convincing reports demonstrating the ability of PPRV to cross the species barrier. Indeed, PPRV can infect animal species other than small ruminants, with dromedaries, wild goats, pigs and cattle reportedly being identified with PPRV [12][13][14][15][16]. It is currently unclear whether these infections are relevant from an epidemiological and eradication perspective; however, it is essential to fully understand the role of wildlife in the spread and potential maintenance of PPRV in the environment in order to be able to initiate successful control strategies.…”

Section: Infection Of Wildlife and Other Speciesmentioning

confidence: 99%

“…The importance of this research was highlighted by a recent outbreak in Mongolia. In December 2016 the disease was diagnosed in several wildlife populations in the East of the country, including saiga antelope (Saiga tatarica mongolica), ibex (Capra sibirica) and goitered gazelle (Gazella subguttorosa), with more than 80% mortality of the 10,000, highly endangered saiga population of the country [12,16]. Studies in camel populations, kept together with small ruminants, in the Isiolo, Mandera, Marsabit, and Wajir counties of Kenya, established that camels in the study area suffer with PPR manifesting clinical signs that are mainly characterized by inappetence, loss of body condition, and general weakness, leading to diarrhea, conjunctivitis, and ocular nasal discharges preceding death.…”

Section: Infection Of Wildlife and Other Speciesmentioning

confidence: 99%

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Eradicating the Scourge of Peste Des Petits Ruminants from the World

Njeumi

Bailey

Soula

et al. 2020

Viruses

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Peste des Petits Ruminants (PPR) is a highly contagious viral disease of both domestic (goats and sheep) and wild ruminants. Caused by a morbillivirus, that belongs to the family Paramyxoviridae. The disease is clinically and pathologically similar to rinderpest of cattle and human measles. PPR is one of the most economically devastating viral diseases of small ruminants. In April 2015, the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE) launched the PPR Global Control and Eradication Strategy (PPR GCES) with the vision for global eradication by 2030. There is a strong and lasting international consensus to eradicate the disease in order to protect the livelihoods of the world’s poorest populations. As with any disease, eradication is feasible when, policy, scientific and technical challenges are addressed. Ten majors challenges are described in this paper namely: understanding small ruminant production, facilitating research to support eradication, refining laboratory testing, improving epidemiological understanding of the virus, defining infection of wildlife and other species, optimizing vaccine delivery and novel vaccines, developing better control of animal movement, heightening serological monitoring, understanding socio-economic impact, and garnering funding and political will.

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“…Peste des petits ruminants (PPR) is a highly contagious transboundary disease caused by the Peste des petits ruminants virus (PPRV) [1][2][3]. PPRV belongs to the morbillivirus genus, Paramyxoviridae family [4] and has been renamed as small ruminant morbillivirus (SRMV) by the International Committee on Taxonomy of Viruses in 2016 [5].…”

Section: Introductionmentioning

confidence: 99%

Progress towards Eradication of Peste des Petits Ruminants through Vaccination

Zhao

Njeumi

Parida

et al. 2021

Viruses

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Peste des petits ruminants (PPR) is a transboundary viral disease that threatens more than 1.74 billion goats and sheep in approximately 70 countries globally. In 2015, the international community set the goal of eradicating PPR by 2030, and, since then, Food and Agriculture Organization of the United Nations (FAO) and World Organization for Animal Health (OIE) have jointly developed and implemented the Global Control and Eradication Strategy for PPR. Here, data from the United Nations Food and Agriculture Organization Statistical Database (FAOSTAT), the OIE World Animal Health Information System (WAHIS), Regional Roadmap Meetings, and countries’ responses to PPR Monitoring and Assessment Tool (PMAT) questionnaires were analyzed to inform on current progress towards PPR eradication. OIE recorded the use of over 333 million doses of vaccine in 12 countries from 2015 to 2018, 41.8% of which were used in Asia and 58.2% in Africa. Between 2015 and 2019, a total of 12,757 PPR outbreaks were reported to OIE: 75.1% in Asia, 24.8% in Africa, and 0.1% in Europe. The number of global outbreaks in 2019 fell to 1218, compared with 3688 in 2015. Analysis of vaccine use and PPR outbreaks in countries indicates that disease control strategies, particularly vaccination campaigns and vaccine distribution strategies, still require scientific evaluation. It is imperative that vaccination is undertaken based on the epidemiology of the disease in a region and is coordinated between neighboring countries to restrict transboundary movements. Strengthening surveillance and post-vaccination sero-monitoring at the national level is also essential. The PPR vaccine stock/bank established by FAO, OIE, and other partners have improved the quality assurance and supply of vaccines. However, to achieve PPR eradication, filling the funding gap for vaccination campaigns and other program activities will be critical.

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Eradication of Peste des Petits Ruminants Virus and the Wildlife-Livestock Interface

Cited by 49 publications

References 46 publications

Serosurvey of Peste des Petits Ruminants in southern Spain

Serosurvey of Peste des Petits Ruminants in southern Spain

Eradicating the Scourge of Peste Des Petits Ruminants from the World

Progress towards Eradication of Peste des Petits Ruminants through Vaccination

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