Erectile Dysfunction in Chronic Hemodialysis Patients in Dakar: a Cross-Sectional Study in 2012

Abstract

Background:Patients with chronic kidney disease (CKD) experience multiple complications including erectile dysfunction (ED). It involves more than 50% of patients on dialysis or transplant. In Africa, the true extent of ED in CKD is unknown although some studies have been done in this regard.Objectives:This study aimed to determine the prevalence and identify risk factors of ED in patients on hemodialysis.Patients and Methods:This cross-sectional multicenter study was conducted from January 2, 2012 through April 30, 2012 in four hemodialysis centers in Dakar. We included all patients on chronic hemodialysis who aged ≥ 18 years old and freely consented to participate in the study. Sociodemographic, clinical, and hemodialysis data were collected through a questionnaire. Erectile function was assessed by a short version of International Index of Erectile Function (IIEF-5).Results:Among a target of 80 patients, 73 met the inclusion criteria and were included in this study. Mean dialysis vintage was 27.3 months (range, 1-156). Their mean age was 53.81 ± 12.52 years, with a higher proportion of age group of 50 to 69 years old. Fifty-six patients were married (37 monogamous and 19 polygamous) and six were singles. Overall prevalence of ED was 84.9% and it was severe in 14 patients (19.2%). Hypertension and diabetes were the most frequent etiologies and antihypertensive treatment was used in 95.5%. The main factors associated with ED were age > 50 years old and polygamy.Conclusions:ED is a common problem among patients on hemodialysis in Dakar with a high prevalence. Aging and diabetes represent most common causes. More efforts are needed for its early detection, prevention, and multidisciplinary management.

Prevalence and Erectile Dysfunction-Associated Factors in Chronic Haemodialysis Patients in 2 Semi Urban Centres in Senegal

“…The prevalence in this population varies from 41.5% to 82% [4,5] and is significantly higher in CKD stage 5 patients than in stage 3 and 4 patients [6]. Previous studies in Senegal reported prevalences of 80% and 84.9% in chronic haemodialysis patients [7,8]. In the literature, some factors such as age, duration of dialysis, hypertension, diabetes, hormonal disorders, etc.…”

The efficacy of low-dose tadalafil in patients undergoing hemodialysis with end-stage renal disease

“…Psychogenic causes are another etiological reason in ESRD patients compared to age-matched counterparts without renal failure [44]. According to the World Health Organization, the prevalence of depression is approximately 16% [45].…”