ERG findings in three hypothyroid adult dogs with and without levothyroxine treatment

Durieux, Philippe; Rigaudière, Florence; Legargasson, J. F.; Rosolen, Serge G.

doi:10.1111/j.1463-5224.2008.00656.x

Cited by 5 publications

(5 citation statements)

References 24 publications

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“…The perfect stability of retinal exposure to light cannot be guaranteed during the adaptation period, as the animals were not anaesthetized, and blinking was still possible. A longer acclimation period may have been necessary for complete light adaptation, as proposed in other studies and species 14 …”

Section: Discussionmentioning

confidence: 72%

“…Photopic and scotopic electroretinogram recordings were successfully conducted on anaesthetized minipigs using Lazard sclerocorneal clip electrodes. Previous studies have described the use of this type of clip electrode (including on minipigs), albeit at a far lesser scale 14,19,21,22 . This type of electrode allows the animal’s head and globes to be maintained in a stable position during the entire examination.…”

Section: Discussionmentioning

confidence: 99%

“…The purpose of these guidelines is to propose standardized and reproducible protocols for electroretinographic examination. Many steps of these protocols are subject to variations because of the variety of options available to operators within the parameters of the stimulation technique or depending on the purpose of the examination 8–14 …”

Section: Introductionmentioning

confidence: 99%

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Recording of the full‐field electroretinogram in minipigs

Augsburger¹,

Haag²,

Leuillet³

et al. 2012

Veterinary Ophthalmology

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Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Recording of the full‐field electroretinogram in minipigs

Augsburger¹,

Haag²,

Leuillet³

et al. 2012

Veterinary Ophthalmology

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“…Binocular ERGs were evoked with the use of two bright flashes of light (Xenon capacitive discharge adjustable photostimulators with 20 ls of stimulus duration) delivered in full-field conditions as previously reported [41,42]. Sclero-conjunctival copper clips attached to the conjunctiva of the superior part of the globe.…”

Section: Erg Proceduresmentioning

confidence: 99%

Effects of hypercapnia on the electroretinogram in sevoflurane and isoflurane anaesthetized dogs

Varela

Vazquez

González‐Cantalapiedra

et al. 2010

Doc Ophthalmol

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To evaluate the effects of induced hypercapnia on the electroretinogram (ERG) in beagle dogs anaesthetized with isoflurane and sevoflurane. Binocular, full-field flash photopic and scotopic ERGs were obtained from six healthy neutered female beagle dogs. In order to determine Vmax and the photopic negative response (PhNR), photopic ERG luminance-response curves were generated with 17 different light stimuli. Photopic flicker ERGs were obtained at 30-Hz temporal frequency. Scotopic ERGs were recorded after 35 min of dark adaptation. For all animals, this procedure was performed once in four different sessions: isoflurane + end-tidal [CO(2)] at 35 mmHg +/- 3 mmHg (ISON), isoflurane + end-tidal [CO(2)] at 65 mmHg +/- 3 mmHg (ISOH), sevoflurane + end-tidal [CO(2)] at 35 mmHg +/- 3 mmHg (SEVON), isoflurane + end-tidal [CO(2)] at 65 mmHg +/- 3 mmHg (SEVOH). In photopic conditions, b-wave amplitudes were significantly smaller in hypercapnic groups (ISON = 170.6 +/- 12.1 microV; ISOH = 132.6 +/- 24.9 microV; SEVON = 170.9 +/- 14.4 microV; SEVOH = 130.2 +/- 22.8 microV). Similarly, in scotopic conditions, b-wave amplitudes were significantly decreased when CO(2) was increased (ISON = 89.4 +/- 14.7 microV; ISOH = 58.2 +/- 17.6 microV; SEVON = 93.4 +/- 24.1 microV; SEVOH = 56.2 +/- 22.2 microV). Flicker peak times were significantly increased in hypercapnic groups (ISON = 25.9 +/- 0.4 ms; ISOH = 27.7 +/- 1.2 ms; SEVON = 25.9 +/- 1.5 ms; SEVOH = 27.2 +/- 0.7 ms). Our results clearly indicate that induced hypercapnia significantly alters the genesis of the electroretinogram at level of ON-pathway and suggest that OFF-pathway is unaffected and that ERGs obtained from isoflurane or sevoflurane anaesthetized dogs are almost identical. Control of hypercapnia must be taken into consideration when ERGs are performed under inhaled anaesthesia in dogs.

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“…La prise d'hormones thyroïdiennes peut retentir sur le fonctionnement rétinien et entraîner une diminution des temps de culmination des ondes aussi bien des systèmes photopique que scotopique [Durieux et al, 2008].…”

Section: Autres…unclassified