Erratum à l’article « Analysis of the 2015 British guidelines on the prevention and management of tumor lysis syndrome » [Rev. Med. Interne 38 (2017) 36–43]

Dupré, Aurélien; Mousseaux, Cyril; Bouguerba, Abdelaziz; Ayed, Soufia; Barchazs, J.; Boukari, M.; Goldgran-Tolédano, Dany; Bornstain, Caroline; Vincent, François

doi:10.1016/j.revmed.2017.01.017

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2020

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“…It is important to supply liquids (3 l per day) and to start a treatment with Allopurinol or better Uratoxidase (Rasburicase) as a prophylactic treatment. The main goal of treatment is to prevent the occurrence of renal dysfunction which is associated with heavy morbidity and mortality [6].…”

Section: Discussionmentioning

confidence: 99%

Metastatic choriocarcinoma with tumour lysis syndrome

Osorio¹,

Männle²,

Münstedt³

2020

Clin Case Rep Rev

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We report on a 32-year-old woman, gravida 5, para 2 who presented with a rapidly growing process of a choriocarcinoma after spontaneous birth. Two weeks after delivery, the patient suffered from dyspnoe, tachycardia and two large ovarian cysts. Diagnostic showed a metastasis choriocarcinoma in the lung. After the first application of chemotherapy according to the EMACO protocol the patient degraded quickly. She had a respiratory distress syndrome and an endotracheal intubation was necessary. We suspected a massive tumour cell lysis with haemorrhage after chemotherapy. Tumourlysis syndrome in choriocarcinoma is a rare complication as it is in solid tumours. Treatment in the intensive care unit allowed continuation of chemotherapy with EMACO. The general health state of the patient improves slowly and ß-HCG falled. After 78 days of hospitalization the patient was able to be discharged from hospital.

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Section: Discussionmentioning

confidence: 99%