Erratum: Lipid membrane-mediated attraction between curvature inducing objects

Wel, Casper van der; Vahid, Afshin; Šarić, Anđela; Idema, Timon; Heinrich, Doris; Kraft, Daniela J.

doi:10.1038/srep37382

Cited by 10 publications

(17 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The current paper demonstrates how the flat, stiff nature of solid plate-like domains, forcing curvature into the fluid membranes of vesicles, produces unique features in solid domain interactions that are distinct from the interactions between coexisting fluid domains in well-studied lipid mixtures (3)(4)(5), or colloid and protein-scale membrane inclusions (6)(7)(8)27). These differences include solid domain interactions that are both attractive and repulsive, and the ability to toggle interactions by osmotic adjustments or mechanical manipulation of the fluid portion of the membrane.…”

Section: Introductionmentioning

confidence: 91%

Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids

Xin

Grason

et al. 2021

Sci. Adv.

View full text Add to dashboard Cite

We demonstrate how manipulating curvature in an elastic fluid lamella enables the reversible relative positioning of flat, rigid, plate-like micrometer-scale inclusions, with spacings from about a micrometer to tens of micrometers. In an experimental model comprising giant unilamellar vesicles containing solid domain pairs coexisting in a fluid membrane, we adjusted vesicle inflation to manipulate membrane curvature and mapped the interdomain separation. A two-dimensional model of the pair potential predicts the salient experimental observations and reveals both attractions and repulsions, producing a potential minimum entirely a result of the solid domain rigidity and bending energy in the fluid membrane. The impact of vesicle inflation on domain separation in vesicles containing two solid domains was qualitatively consistent with observations in vesicles containing many domains. The behavior differs qualitatively from the pure repulsions between fluid membrane domains or interactions between nanoscopic inclusions whose repulsive or attractive character is not switchable.

show abstract

Section: Introductionmentioning

confidence: 91%

Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids

Xin

Grason

et al. 2021

Sci. Adv.

View full text Add to dashboard Cite

show abstract

“…This suffices to construct an elastic energy function associated with membrane bending that allows us to obtain the surface equilibrium configurations using numerical update algorithms. In this work, we have employed the Metropolis Monte Carlo algorithm (Ramakrishnan et al, 2010; Bahrami et al, 2012; van der Wel et al, 2016), but many other updating schemes are possible (Noguchi and Takasu, 2001; Cooke et al, 2005; Noguchi and Gompper, 2006; Peng et al, 2013; Mauer et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

A Multi-Scale Approach to Membrane Remodeling Processes

Pezeshkian

König

Marrink

et al. 2019

Front. Mol. Biosci.

View full text Add to dashboard Cite

We present a multi-scale simulation procedure to describe membrane-related biological processes that span over a wide range of length scales. At macroscopic length-scale, a membrane is described as a flexible thin film modeled by a dynamic triangulated surface with its spatial conformations governed by an elastic energy containing only a few model parameters. An implicit protein model allows us to include complex effects of membrane-protein interactions in the macroscopic description. The gist of this multi-scale approach is a scheme to calibrate the implicit protein model using finer scale simulation techniques e.g., all atom and coarse grain molecular dynamics. We previously used this approach and properly described the formation of membrane tubular invaginations upon binding of B-subunit of Shiga toxin. Here, we provide a perspective of our multi-scale approach, summarizing its main features and sketching possible routes for future development.

show abstract

“…By combining several approaches, additional insight may be gained and complementary pictures emerge as in the study of the formation of liquid ordered domains combining confocal microscopy with fluorescence microscopy and AFM [101]. In some cases, the dynamics of objects can be tracked in 3 dimensions [102,103].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Visualizing Biological Membrane Organization and Dynamics

Baaden

2019

Journal of Molecular Biology

View full text Add to dashboard Cite

Biological membranes are fascinating. Santiago Ramón y Cajal, who received the Nobel prize in 1906 together with Camillo Golgi for their work on the nervous system, wrote "[..]in the study of this membrane[..] I felt more profoundly than in any other subject of study the shuddering sensation of the unfathomable mystery of life" 1 . The visualization and conceptualization of these biological objects have profoundly shaped many aspects of modern biology, drawing inspiration from experiments, computer simulations, as well as from the imagination of scientists and artists. The aim of this review is to provide a fresh look on current ideas of biological membrane organization and dynamics by discussing selected examples across fields.

show abstract

Erratum: Lipid membrane-mediated attraction between curvature inducing objects

Cited by 10 publications

References 0 publications

Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids

Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids

A Multi-Scale Approach to Membrane Remodeling Processes

Visualizing Biological Membrane Organization and Dynamics

Contact Info

Product

Resources

About