ERS position paper: work-related respiratory diseases in the EU

Sigsgaard, Torben; Nowak, Dennis; Annesi‐Maesano, Isabella; Nemery, Benoît; Torén, Kjell; Viegi, Giovanni; Radon, Katja; Burge, Sherwood; Heederik, Dick

doi:10.1183/09031936.00139409

Cited by 32 publications

(21 citation statements)

References 32 publications

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“…Even in economically advanced countries, occupational exposures to gases and vapours, mineral and organic dusts, or infectious agents still constitute substantial risks of both specific and nonspecific lung disease [42]. Thus, it has been estimated that occupational exposures contribute to 15% of cases of asthma or COPD in industrial countries [43][44][45].…”

mentioning

confidence: 99%

The European Union conference on chronic respiratory disease: purpose and conclusions

Decramer¹,

Sibille²,

Bush³

et al. 2011

Eur Respir J

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mentioning

confidence: 99%

The European Union conference on chronic respiratory disease: purpose and conclusions

Decramer¹,

Sibille²,

Bush³

et al. 2011

Eur Respir J

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“…Im Positionspapier der "European Respiratory Society" [17] wird der Populations-attribuierbare Anteil beruflicher Expositionen an der Entstehung der COPD auf 15 -20 %, und damit deutlich höher als in älteren Studien, geschätzt. Systematische Reviews waren Grundlage eines kürzlich erschienenen Public Policy Statement der "American Thoracic Society" [2], inzwischen erschien in zwei neueren Originalarbeiten [4,12] und einem weiteren systematischen Review [11] noch unterstützende Evidenz hierzu.…”

Section: Copd Und Beruf ▼unclassified

Pneumologische Arbeits- und Umweltmedizin

Ochmann

Nowak

2012

Dtsch med Wochenschr

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“…Respiratory diseases rank as the third most prevalent work-related diseases (after ergonomic and stress-related diseases) according to a survey of occupational diseases in the European Union [1]. Workrelated asthma (WRA) is the most common work-related lung disease in the last decades, causing significant morbidity, disability and high costs [2].…”

Section: Introductionmentioning

confidence: 99%

Distribution of Sensitizer-Induced Occupational Asthma

Минов¹

2015

Glob J Allergy

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Introduction: Occupational asthma (OA) became an important public health problem worldwide in the last few decades. From two different OA types, sensitizer-induced OA accounts for approximately 90% of all OA cases. Aim of the study was to present the distribution of sensitizer-induced OA by occupation in R. Macedonia in the period 2005-2014.Methods: Sensitizer-induced OA was diagnosed by serial measurement of peak expiratory flow (PEF) at and away from work or by combination of serial PEF measurement at and away from work and non-specific bronchial provocation at and away from work in subjects with diagnosed asthma and work-relatedness of the symptoms. Results:The annual incidence rate of the diagnosed sensitizer-induced OA in the mentioned period varied from 1.8/100,000 working population in 2013 to 2.8/100,000 in 2006. Sensitizer-induced OA in bakers, cleaners, textile workers and agricultural workers accounted up to more than a third of the all diagnosed cases. Atopy was registered in approximately a half of the sensitized-induced OA cases. Majority of the cases with sensitizer-induced OA caused by HMW agents (i.e. OA in bakers, textile workers, tanners, herbal and fruit tea processors, and health care workers) was atopics and had positive prick tests to occupational allergens. sensitizer-induced and irritant-induced OA. Sensitizer-induced OA, which accounts for approximately 90% of all OA cases, is characterized by a latency period between first exposure to a respiratory sensitizer at work and the first presentation of symptoms, while irritantinduced OA starts typically within a few hours of a high-intensity exposure to an irritant gas, fumes or vapor encountered at work [3]. More than 250 occupational sensitizers causing OA have been described. According to their molecular weight these occupational agents are categorized into high-molecular-weight (HMW) agents (e.g. animal and plant proteins, flour and grain dust, latex, etc.) and low-molecular-weight (LMW) reactive chemicals (e.g. isocyanates, colophony, aldehydes, metal salts, etc.) Sensitization to most HMW and some LMW agents is through an immunoglobuline E (IgE) mechanisms and can be tested by skin tests, while most LMW agents cause allergic sensitization through IgE-independent mechanisms and an allergen-specific immune response can not be documented by skin tests [7]. ConclusionA recent meat-analysis indicates that occupational factors account for approximately one in six cases of asthma in adults of working age [8]. The incidence of OA within the workforce depends on people's jobs and the workplace hazards to which they are exposed. The aim

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ERS position paper: work-related respiratory diseases in the EU

Cited by 32 publications

References 32 publications

The European Union conference on chronic respiratory disease: purpose and conclusions

The European Union conference on chronic respiratory disease: purpose and conclusions

Pneumologische Arbeits- und Umweltmedizin

Distribution of Sensitizer-Induced Occupational Asthma

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