The trachydacitic Alpehué tephra from Sollipulli volcano (Andean Southern Volcanic Zone), consists of ignimbrite and fallout from a Plinian eruption about 3000 years ago. It is mainly composed of (1) crystal-rich pumice and ash but also contains (2) chilled knobbly basaltic lava clasts and (3) mostly highly inflated glomerocrystic fragments with high crystal-glass ratios interpreted to represent a crystal mush zoned from basaltic to dacitic bulk compositions. Knobbly lava clasts are of three types: (a) a very phenocryst-poor basalt, (b) a basalt with large, unzoned olivine and plagioclase phenocrysts and glomerocrysts, and (c) mixtures of microcrystalline basalt with various fragments, glomerocrysts and crystals derived from a crystal mush. Clast type (4) in the tephra is banded pumices in which the three magmatic components occur variably mingled. Thermobarometry and petrographic observations, particularly presence or absence of amphibole, constrain an upper-crustal succession of a lower basaltic reservoir, a zoned basaltic to dacitic crystal mush reservoir, and a separate trachydacite magma chamber on top. All Alpehué magmatic components form a coherent liquid line of descent which supports the interpretation that the crystal mush reservoir is a gradually solidifying magma chamber, not the result of large-scale crystal-liquid segregation. The trachydacite magma may originally have formed as melt escaping from the crystal-mush reservoir but subsequently underwent a long and complex evolution recorded in large strongly zoned plagioclase phenocrysts including resorption horizons. The ascending mafic magmas collected samples from the crystal mush body and intruded the trachydacite reservoir. The phenocryst-poor basalt (a) arrived first and entrained and partially resorbed plagioclase from the host magma. The phyric basalt (b) arrived later and did not resorb entrained plagioclase before eruption. Estimated cooling times, plagioclase resorption times and ascent rates avoiding amphibole breakdown limit the duration of these pre-eruptive processes to not more than a few days.