Eruptive pigmented patches in a patient with HIV infection under HAART

Abstract

Introduction: Highly active antiretroviral therapy (HAART) is a standard treatment for HIV-infected patients. It has been reported that emtricitabine rarely induces skin pigmentation in the palms and soles. We herein report a Japanese case which presented a number of small pigmented patches on the acral sites. Main observation: A 58-year-old Japanese man complained about multiple brownish skin pigmentations on his both palms and soles after 2 months of HAART therapy. Dermatoscopic observation showed a homogeneous light brown pattern. In spite of continuance of HAART, these lesions spontaneously regressed within 11 months. Conclusion:We should know about the eruptive pigmented patches as an adverse effect under HAART with HIV infected patients.