“…Adults are less likely to manifest oral involvement than children 4 , and the patient in this case did not also have perioral lesions, only showing targetoid macular eruption predominant in trunk. Similarly, a previous report showed targetoid macules and vesicles imitating EM in adult-onset HFMD but with oral mucosal ulcers 5 . In our case, serologic analysis confirmed co-infection of atypical strains Coxsackievirus A6 and A10 with the common strain A16.…”