Erythema nodosum

Leung, Alexander K C; Leong, Kin Fon; Lam, Joseph M.

doi:10.1007/s12519-018-0191-1

Cited by 60 publications

(84 citation statements)

References 54 publications

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“…EN may correlate with various inflammatory diseases. [19][20][21][22][23] In clinical practice, IMNM can be listed as an EN-associated entity. Our case also indicates that the IMNM and EN might have overlapping pathogeneses.…”

Section: Discussionmentioning

confidence: 99%

“…Including infection (eg, Streptococcus spp, Mycobacterium tuberculosis), drug, malignancy, inflammatory bowel disease, autoimmune atrophic gastritis, sarcoidosis, pregnancy and other causes. [19][20][21][22][23] Here we present a case of IMNM that started with acute EN before the development of a subtype of IMNM identified by anti-SRP antibody, followed by significant clinical improvement after the initiation of glucocorticoids, intravenous immunoglobulin (IVIG), rituximab and mycophenolate mofetil. The report was approved by the ethics committee of the First Affiliated Hospital, Zhejiang University School of Medicine (Approved number: 2020-ITT-356) prior to study commencement.…”

Section: Introductionmentioning

confidence: 99%

“…[15][16][17] Erythema nodosum (EN) is a common form of acute nodular septal panniculitis without signs of vasculitis. [18][19][20][21][22] It is clinically characterized by bilaterally symmetrical red and painful subcutaneous nodules, mainly localized to the lower extremities, pretibial areas especially. 18,19 EN is often associated with multisystemic diseases, including autoimmune diseases and hypersensitivity reactions in response to antigens or triggers.…”

Section: Introductionmentioning

confidence: 99%

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<p>Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum</p>

Ying¹,

Li²,

Tang³

et al. 2020

JIR

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Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by severe diffuse proximal myofiber necrosis in the context of inflammatory myopathy. Autoantibodies of anti-signal recognition particle and anti-hydroxy-3-methylglutaryl-CoA reductase are two antibodies specific to IMNM. Erythema nodosum (EN) is often accompanied by various systemic diseases, such as autoimmune diseases. Herein, we report a female patient with signal recognition particle-associated IMNM, with EN as the first presentation. She showed significant clinical improvement after the initiation of glucocorticoids, intravenous immunoglobulin, rituximab, and mycophenolate mofetil. This case indicates that IMNM can initially present as EN. IMNM and EN might have overlapping pathogeneses.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum</p>

Ying¹,

Li²,

Tang³

et al. 2020

JIR

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“… 16 The differential diagnosis includes erythema nodosum, ecchymosis, minocycline dyspigmentation, and erysipelas. 17 The color, chronicity, and associated HCQ use help to distinguish HCQ-induced hyperpigmentation from these other disorders. There are no formal criteria for HCQ-induced hyperpigmentation as the diagnosis is usually clinically apparent.…”

Section: Discussionmentioning

confidence: 99%

Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus

Leung

McMillan

Human

et al. 2020

DIC

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Hydroxychloroquine (HCQ)-induced hyperpigmentation is uncommon but is increasingly recognized. To our knowledge, HCQ-induced hyperpigmentation has not been reported in the pediatric age group. Herein, we present the case of a 14-year-old girl with systemic lupus erythematosus, who developed hyperpigmentation on her shins and dorsum of the left foot, approximately 3 years after initiating treatment with HCQ. Physicians who treat children with HCQ for reasons such as rheumatologic disorders, dermatologic disorders and, more recently, coronavirus disease-19 should be aware of this less-known side effect of HCQ.

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“…The worldwide prevalence of EN is estimated at 1-5/100,000 persons. It usually affects individuals aged 18 to 34 years, and is more common among women (3-5:1) (1) . EN was observed to be seasonal, with a higher number of cases in the period from spring to autumn, which may be related to the increased prevalence of streptococcal infections during this time (2) .…”

Section: Introductionmentioning

confidence: 99%

Erythema nodosum in a child with Salmonella Enteritidis infection

Kamińska-Sobczak¹,

Karska²,

Lange³

et al. 2021

Pediatr Med Rodz

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The paper discusses a case of erythema nodosum in an almost 2-year-old boy diagnosed for fever and skin lesions on the extensor parts of the lower legs. Extended medical history and diagnosis allowed to identify Salmonella Enteritidis as the culprit of symptoms. This entity is rarely found in the paediatric population, especially in children <2 years of age. It clinically manifests with small, painful, red to purple subcutaneous nodules, mostly developing in the lower extremities. Only few cases of correlation between erythema nodosum and this serotype of Salmonella have been described in the available literature. Reminding general practitioners and paediatricians of the basic information about the possible course of the disease will allow for earlier differential diagnosis and more rapid and appropriate treatment.

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Erythema nodosum

Cited by 60 publications

References 54 publications

<p>Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum</p>

<p>Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum</p>

Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus

Erythema nodosum in a child with Salmonella Enteritidis infection

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